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The EU-ToxRisk method documentation, data processing and chemical testing pipeline for the regulatory use of new approach methods.
Krebs A, van Vugt-Lussenburg BMA, Waldmann T, Albrecht W, Boei J, Ter Braak B, Brajnik M, Braunbeck T, Brecklinghaus T, Busquet F, Dinnyes A, Dokler J, Dolde X, Exner TE, Fisher C, Fluri D, Forsby A, Hengstler JG, Holzer AK, Janstova Z, Jennings P, Kisitu J, Kobolak J, Kumar M, Limonciel A, Lundqvist J, Mihalik B, Moritz W, Pallocca G, Ulloa APC, Pastor M, Rovida C, Sarkans U, Schimming JP, Schmidt BZ, Stöber R, Strassfeld T, van de Water B, Wilmes A, van der Burg B, Verfaillie CM, von Hellfeld R, Vrieling H, Vrijenhoek NG, Leist M. Krebs A, et al. Among authors: schimming jp. Arch Toxicol. 2020 Jul;94(7):2435-2461. doi: 10.1007/s00204-020-02802-6. Epub 2020 Jul 6. Arch Toxicol. 2020. PMID: 32632539 Free PMC article.
Mapping the cellular response to electron transport chain inhibitors reveals selective signaling networks triggered by mitochondrial perturbation.
van der Stel W, Yang H, Vrijenhoek NG, Schimming JP, Callegaro G, Carta G, Darici S, Delp J, Forsby A, White A, le Dévédec S, Leist M, Jennings P, Beltman JB, van de Water B, Danen EHJ. van der Stel W, et al. Among authors: schimming jp. Arch Toxicol. 2022 Jan;96(1):259-285. doi: 10.1007/s00204-021-03160-7. Epub 2021 Oct 13. Arch Toxicol. 2022. PMID: 34642769 Free PMC article.
Protectiveness of NAM-based hazard assessment - which testing scope is required?
Zobl W, Bitsch A, Blum J, Boei JJWA, Capinha L, Carta G, Castell J, Davoli E, Drake C, Fisher CP, Heldring MM, Islam B, Jennings P, Leist M, Pellegrino-Coppola D, Schimming JP, Snijders KE, Tolosa L, van de Water B, van Vugt-Lussenburg BMA, Walker P, Wehr MM, Wijaya LS, Escher SE. Zobl W, et al. Among authors: schimming jp. ALTEX. 2024;41(2):302-319. doi: 10.14573/altex.2309081. Epub 2023 Dec 4. ALTEX. 2024. PMID: 38048429 Free article.
Identifying multiscale translational safety biomarkers using a network-based systems approach.
Callegaro G, Schimming JP, Piñero González J, Kunnen SJ, Wijaya L, Trairatphisan P, van den Berk L, Beetsma K, Furlong LI, Sutherland JJ, Mollon J, Stevens JL, van de Water B. Callegaro G, et al. Among authors: schimming jp. iScience. 2023 Jan 31;26(3):106094. doi: 10.1016/j.isci.2023.106094. eCollection 2023 Mar 17. iScience. 2023. PMID: 36895646 Free PMC article.