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Identification and Characterization of a Novel Indoleamine 2,3-Dioxygenase 1 Protein Degrader for Glioblastoma.
Bollu LR, Bommi PV, Monsen PJ, Zhai L, Lauing KL, Bell A, Kim M, Ladomersky E, Yang X, Platanias LC, Matei DE, Bonini MG, Munshi HG, Hashizume R, Wu JD, Zhang B, James CD, Chen P, Kocherginsky M, Horbinski C, Cameron MD, Grigorescu AA, Yamini B, Lukas RV, Schiltz GE, Wainwright DA. Bollu LR, et al. Among authors: schiltz ge. J Med Chem. 2022 Dec 8;65(23):15642-15662. doi: 10.1021/acs.jmedchem.2c00771. Epub 2022 Nov 21. J Med Chem. 2022. PMID: 36410047 Free PMC article.
Syntheses of FDA Approved HIV Protease Inhibitors.
Ghosh AK, Bilcer G, Schiltz G. Ghosh AK, et al. Synthesis (Stuttg). 2001;2001(15):2203-2229. doi: 10.1055/s-2001-18434. Synthesis (Stuttg). 2001. PMID: 30393404 Free PMC article.
Virtual High-Throughput Screening To Identify Novel Activin Antagonists.
Zhu J, Mishra RK, Schiltz GE, Makanji Y, Scheidt KA, Mazar AP, Woodruff TK. Zhu J, et al. Among authors: schiltz ge. J Med Chem. 2015 Jul 23;58(14):5637-48. doi: 10.1021/acs.jmedchem.5b00753. Epub 2015 Jul 7. J Med Chem. 2015. PMID: 26098096 Free PMC article.
Cancer-Associated IDH1 Promotes Growth and Resistance to Targeted Therapies in the Absence of Mutation.
Calvert AE, Chalastanis A, Wu Y, Hurley LA, Kouri FM, Bi Y, Kachman M, May JL, Bartom E, Hua Y, Mishra RK, Schiltz GE, Dubrovskyi O, Mazar AP, Peter ME, Zheng H, James CD, Burant CF, Chandel NS, Davuluri RV, Horbinski C, Stegh AH. Calvert AE, et al. Among authors: schiltz ge. Cell Rep. 2017 May 30;19(9):1858-1873. doi: 10.1016/j.celrep.2017.05.014. Cell Rep. 2017. PMID: 28564604 Free PMC article.
Development of GLUT4-selective antagonists for multiple myeloma therapy.
Wei C, Bajpai R, Sharma H, Heitmeier M, Jain AD, Matulis SM, Nooka AK, Mishra RK, Hruz PW, Schiltz GE, Shanmugam M. Wei C, et al. Among authors: schiltz ge. Eur J Med Chem. 2017 Oct 20;139:573-586. doi: 10.1016/j.ejmech.2017.08.029. Epub 2017 Aug 14. Eur J Med Chem. 2017. PMID: 28837922 Free PMC article.
Small Molecules Target the Interaction between Tissue Transglutaminase and Fibronectin.
Sima LE, Yakubov B, Zhang S, Condello S, Grigorescu AA, Nwani NG, Chen L, Schiltz GE, Arvanitis C, Zhang ZY, Matei D. Sima LE, et al. Among authors: schiltz ge. Mol Cancer Ther. 2019 Jun;18(6):1057-1068. doi: 10.1158/1535-7163.MCT-18-1148. Epub 2019 Apr 23. Mol Cancer Ther. 2019. PMID: 31015308 Free PMC article.
45 results