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The antidepressant Sertraline inhibits CatSper Ca2+ channels in human sperm.
Rahban R, Rehfeld A, Schiffer C, Brenker C, Egeberg Palme DL, Wang T, Lorenz J, Almstrup K, Skakkebaek NE, Strünker T, Nef S. Rahban R, et al. Among authors: schiffer c. Hum Reprod. 2021 Sep 18;36(10):2638-2648. doi: 10.1093/humrep/deab190. Hum Reprod. 2021. PMID: 34486673 Free PMC article.
Direct action of endocrine disrupting chemicals on human sperm.
Schiffer C, Müller A, Egeberg DL, Alvarez L, Brenker C, Rehfeld A, Frederiksen H, Wäschle B, Kaupp UB, Balbach M, Wachten D, Skakkebaek NE, Almstrup K, Strünker T. Schiffer C, et al. EMBO Rep. 2014 Jul;15(7):758-65. doi: 10.15252/embr.201438869. Epub 2014 May 12. EMBO Rep. 2014. PMID: 24820036 Free PMC article.
Action of steroids and plant triterpenoids on CatSper Ca2+ channels in human sperm.
Brenker C, Schiffer C, Wagner IV, Tüttelmann F, Röpke A, Rennhack A, Kaupp UB, Strünker T. Brenker C, et al. Among authors: schiffer c. Proc Natl Acad Sci U S A. 2018 Jan 16;115(3):E344-E346. doi: 10.1073/pnas.1717929115. Epub 2018 Jan 5. Proc Natl Acad Sci U S A. 2018. PMID: 29305558 Free PMC article. No abstract available.
A novel cross-species inhibitor to study the function of CatSper Ca2+ channels in sperm.
Rennhack A, Schiffer C, Brenker C, Fridman D, Nitao ET, Cheng YM, Tamburrino L, Balbach M, Stölting G, Berger TK, Kierzek M, Alvarez L, Wachten D, Zeng XH, Baldi E, Publicover SJ, Kaupp UB, Strünker T. Rennhack A, et al. Among authors: schiffer c. Br J Pharmacol. 2018 Aug;175(15):3144-3161. doi: 10.1111/bph.14355. Epub 2018 Jun 29. Br J Pharmacol. 2018. PMID: 29723408 Free PMC article.
Molecular Mechanism Underlying the Action of Zona-pellucida Glycoproteins on Mouse Sperm.
Balbach M, Hamzeh H, Jikeli JF, Brenker C, Schiffer C, Hansen JN, Neugebauer P, Trötschel C, Jovine L, Han L, Florman HM, Kaupp UB, Strünker T, Wachten D. Balbach M, et al. Among authors: schiffer c. Front Cell Dev Biol. 2020 Aug 31;8:572735. doi: 10.3389/fcell.2020.572735. eCollection 2020. Front Cell Dev Biol. 2020. PMID: 32984353 Free PMC article.
Human fertilization in vivo and in vitro requires the CatSper channel to initiate sperm hyperactivation.
Young S, Schiffer C, Wagner A, Patz J, Potapenko A, Herrmann L, Nordhoff V, Pock T, Krallmann C, Stallmeyer B, Röpke A, Kierzek M, Biagioni C, Wang T, Haalck L, Deuster D, Hansen JN, Wachten D, Risse B, Behre HM, Schlatt S, Kliesch S, Tüttelmann F, Brenker C, Strünker T. Young S, et al. Among authors: schiffer c. J Clin Invest. 2024 Jan 2;134(1):e173564. doi: 10.1172/JCI173564. J Clin Invest. 2024. PMID: 38165034 Free PMC article.
629 results