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Pathogenetic mechanisms and therapeutic approaches of acute-to-chronic liver failure.
Schierwagen R, Gu W, Brieger A, Brüne B, Ciesek S, Đikić I, Dimmeler S, Geisslinger G, Greten FR, Hermann E, Hildt E, Kempf VAJ, Klein S, Koch I, Mühl H, Müller V, Peiffer KH, Kestner RI, Piiper A, Rohde G, Scholich K, Schulz MH, Storf H, Toptan T, Vasa-Nicotera M, Vehreschild MJGT, Weigert A, Wild PJ, Zeuzem S, Engelmann C; ACLF-I Investigators,; Schaefer L, Welsch C, Trebicka J. Schierwagen R, et al. Am J Physiol Cell Physiol. 2023 Jul 1;325(1):C129-C140. doi: 10.1152/ajpcell.00101.2023. Epub 2023 Jun 5. Am J Physiol Cell Physiol. 2023. PMID: 37273239 Free article. Review.
Atorvastatin inhibits proliferation and apoptosis, but induces senescence in hepatic myofibroblasts and thereby attenuates hepatic fibrosis in rats.
Klein S, Klösel J, Schierwagen R, Körner C, Granzow M, Huss S, Mazar IG, Weber S, van den Ven PF, Pieper-Fürst U, Fürst DO, Nattermann J, Lammert F, Sauerbruch T, Trebicka J. Klein S, et al. Among authors: schierwagen r. Lab Invest. 2012 Oct;92(10):1440-50. doi: 10.1038/labinvest.2012.106. Epub 2012 Aug 13. Lab Invest. 2012. PMID: 22890553 Free article.
Angiotensin-II type 1 receptor-mediated Janus kinase 2 activation induces liver fibrosis.
Granzow M, Schierwagen R, Klein S, Kowallick B, Huss S, Linhart M, Mazar IG, Görtzen J, Vogt A, Schildberg FA, Gonzalez-Carmona MA, Wojtalla A, Krämer B, Nattermann J, Siegmund SV, Werner N, Fürst DO, Laleman W, Knolle P, Shah VH, Sauerbruch T, Trebicka J. Granzow M, et al. Among authors: schierwagen r. Hepatology. 2014 Jul;60(1):334-48. doi: 10.1002/hep.27117. Epub 2014 May 6. Hepatology. 2014. PMID: 24619965 Free PMC article.
Expression of vasoactive proteins in gastric antral mucosa reflects vascular dysfunction in patients with cirrhosis and portal hypertension.
Trebicka J, Wix C, von Heydebrand M, Hittatiya K, Reiberger T, Klein S, Schierwagen R, Kristiansen G, Peck-Radosavljevic M, Fischer HP, Møller S, Bendtsen F, Krag A, Sauerbruch T. Trebicka J, et al. Among authors: schierwagen r. Liver Int. 2015 Apr;35(4):1393-402. doi: 10.1111/liv.12613. Epub 2014 Jul 5. Liver Int. 2015. PMID: 24912856
Seven weeks of Western diet in apolipoprotein-E-deficient mice induce metabolic syndrome and non-alcoholic steatohepatitis with liver fibrosis.
Schierwagen R, Maybüchen L, Zimmer S, Hittatiya K, Bäck C, Klein S, Uschner FE, Reul W, Boor P, Nickenig G, Strassburg CP, Trautwein C, Plat J, Lütjohann D, Sauerbruch T, Tacke F, Trebicka J. Schierwagen R, et al. Sci Rep. 2015 Aug 11;5:12931. doi: 10.1038/srep12931. Sci Rep. 2015. PMID: 26263022 Free PMC article.
Interplay of Matrix Stiffness and c-SRC in Hepatic Fibrosis.
Görtzen J, Schierwagen R, Bierwolf J, Klein S, Uschner FE, van der Ven PF, Fürst DO, Strassburg CP, Laleman W, Pollok JM, Trebicka J. Görtzen J, et al. Among authors: schierwagen r. Front Physiol. 2015 Dec 2;6:359. doi: 10.3389/fphys.2015.00359. eCollection 2015. Front Physiol. 2015. PMID: 26696895 Free PMC article.
106 results