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Supraphysiological FOXP3 expression in human CAR-Tregs results in improved stability, efficacy, and safety of CAR-Treg products for clinical application.
Henschel P, Landwehr-Kenzel S, Engels N, Schienke A, Kremer J, Riet T, Redel N, Iordanidis K, Saetzler V, John K, Heider M, Hardtke-Wolenski M, Wedemeyer H, Jaeckel E, Noyan F. Henschel P, et al. Among authors: schienke a. J Autoimmun. 2023 Jul;138:103057. doi: 10.1016/j.jaut.2023.103057. Epub 2023 May 23. J Autoimmun. 2023. PMID: 37224732 Free article.
Unbalanced translocation der(5;17) resulting in a TP53 loss as recurrent aberration in myelodysplastic syndrome and acute myeloid leukemia with complex karyotype.
Warnstorf D, Bawadi R, Schienke A, Strasser R, Schmidt G, Illig T, Tauscher M, Thol F, Heuser M, Steinemann D, Davenport C, Schlegelberger B, Behrens YL, Göhring G. Warnstorf D, et al. Among authors: schienke a. Genes Chromosomes Cancer. 2021 Jun;60(6):452-457. doi: 10.1002/gcc.22938. Epub 2021 Feb 19. Genes Chromosomes Cancer. 2021. PMID: 33486841
Cdkn1a deletion improves stem cell function and lifespan of mice with dysfunctional telomeres without accelerating cancer formation.
Choudhury AR, Ju Z, Djojosubroto MW, Schienke A, Lechel A, Schaetzlein S, Jiang H, Stepczynska A, Wang C, Buer J, Lee HW, von Zglinicki T, Ganser A, Schirmacher P, Nakauchi H, Rudolph KL. Choudhury AR, et al. Among authors: schienke a. Nat Genet. 2007 Jan;39(1):99-105. doi: 10.1038/ng1937. Epub 2006 Dec 3. Nat Genet. 2007. PMID: 17143283
Author Correction: Cdkn1a deletion improves stem cell function and lifespan of mice with dysfunctional telomeres without accelerating cancer formation.
Choudhury AR, Ju Z, Djojosubroto MW, Schienke A, Lechel A, Schaetzlein S, Jiang H, Stepczynska A, Wang C, Buer J, Lee HW, von Zglinicki T, Ganser A, Schirmacher P, Nakauchi H, Rudolph KL. Choudhury AR, et al. Among authors: schienke a. Nat Genet. 2020 May;52(5):548. doi: 10.1038/s41588-020-0593-6. Nat Genet. 2020. PMID: 32355231
Establishing a murine xenograft-model for long-term analysis of factors inducing chromosomal instability in myelodysplastic syndrome: Pitfalls and successes.
Salari A, Thomay K, Himmler K, Vajen B, Schienke A, Hagedorn M, Ebersold J, Kreipe HH, Krüger A, Schambach A, Schlegelberger B, Göhring G. Salari A, et al. Among authors: schienke a. Cancer Genet. 2016 Jun;209(6):258-66. doi: 10.1016/j.cancergen.2016.04.004. Epub 2016 Apr 22. Cancer Genet. 2016. PMID: 27184732