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The Hsp90 machinery facilitates the transport of diphtheria toxin into human cells.
Schuster M, Schnell L, Feigl P, Birkhofer C, Mohr K, Roeder M, Carle S, Langer S, Tippel F, Buchner J, Fischer G, Hausch F, Frick M, Schwan C, Aktories K, Schiene-Fischer C, Barth H. Schuster M, et al. Sci Rep. 2017 Apr 4;7(1):613. doi: 10.1038/s41598-017-00780-x. Sci Rep. 2017. PMID: 28377614 Free PMC article.
Hsp70 facilitates trans-membrane transport of bacterial ADP-ribosylating toxins into the cytosol of mammalian cells.
Ernst K, Schmid J, Beck M, Hägele M, Hohwieler M, Hauff P, Ückert AK, Anastasia A, Fauler M, Jank T, Aktories K, Popoff MR, Schiene-Fischer C, Kleger A, Müller M, Frick M, Barth H. Ernst K, et al. Among authors: schiene fischer c. Sci Rep. 2017 Jun 2;7(1):2724. doi: 10.1038/s41598-017-02882-y. Sci Rep. 2017. PMID: 28578412 Free PMC article.
Prolyl cis/trans isomerase signalling pathways in cancer.
Theuerkorn M, Fischer G, Schiene-Fischer C. Theuerkorn M, et al. Curr Opin Pharmacol. 2011 Aug;11(4):281-7. doi: 10.1016/j.coph.2011.03.007. Epub 2011 Apr 13. Curr Opin Pharmacol. 2011. PMID: 21497135 Review.
Cyclophilin-facilitated membrane translocation as pharmacological target to prevent intoxication of mammalian cells by binary clostridial actin ADP-ribosylated toxins.
Ernst K, Langer S, Kaiser E, Osseforth C, Michaelis J, Popoff MR, Schwan C, Aktories K, Kahlert V, Malesevic M, Schiene-Fischer C, Barth H. Ernst K, et al. J Mol Biol. 2015 Mar 27;427(6 Pt A):1224-38. doi: 10.1016/j.jmb.2014.07.013. Epub 2014 Jul 21. J Mol Biol. 2015. PMID: 25058685 Free article.
Non-Immunosuppressive Cyclophilin Inhibitors.
Schiene-Fischer C, Fischer G, Braun M. Schiene-Fischer C, et al. Angew Chem Int Ed Engl. 2022 Sep 26;61(39):e202201597. doi: 10.1002/anie.202201597. Epub 2022 Aug 19. Angew Chem Int Ed Engl. 2022. PMID: 35290695 Free PMC article. Review.
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