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Page 1
TLR9 ligand sequestration by chemokine CXCL4 negatively affects central B cell tolerance.
Çakan E, Ah Kioon MD, Garcia-Carmona Y, Glauzy S, Oliver D, Yamakawa N, Vega Loza A, Du Y, Schickel JN, Boeckers JM, Yang C, Baldo A, Ivashkiv LB, Young RM, Staudt LM, Moody KL, Nündel K, Marshak-Rothstein A, van der Made CI, Hoischen A, Hayward A, Rossato M, Radstake TRDJ, Cunningham-Rundles C, Ryu C, Herzog EL, Barrat FJ, Meffre E. Çakan E, et al. Among authors: schickel jn. J Exp Med. 2023 Dec 4;220(12):e20230944. doi: 10.1084/jem.20230944. Epub 2023 Sep 29. J Exp Med. 2023. PMID: 37773045 Free PMC article.
TNF receptor superfamily member 13b (TNFRSF13B) hemizygosity reveals transmembrane activator and CAML interactor haploinsufficiency at later stages of B-cell development.
Romberg N, Virdee M, Chamberlain N, Oe T, Schickel JN, Perkins T, Cantaert T, Rachid R, Rosengren S, Palazzo R, Geha R, Cunningham-Rundles C, Meffre E. Romberg N, et al. Among authors: schickel jn. J Allergy Clin Immunol. 2015 Nov;136(5):1315-25. doi: 10.1016/j.jaci.2015.05.012. Epub 2015 Jun 19. J Allergy Clin Immunol. 2015. PMID: 26100089 Free PMC article.
CD19 controls Toll-like receptor 9 responses in human B cells.
Morbach H, Schickel JN, Cunningham-Rundles C, Conley ME, Reisli I, Franco JL, Meffre E. Morbach H, et al. Among authors: schickel jn. J Allergy Clin Immunol. 2016 Mar;137(3):889-98.e6. doi: 10.1016/j.jaci.2015.08.040. Epub 2015 Oct 21. J Allergy Clin Immunol. 2016. PMID: 26478008 Free PMC article.
Activation-Induced Cytidine Deaminase Expression in Human B Cell Precursors Is Essential for Central B Cell Tolerance.
Cantaert T, Schickel JN, Bannock JM, Ng YS, Massad C, Oe T, Wu R, Lavoie A, Walter JE, Notarangelo LD, Al-Herz W, Kilic SS, Ochs HD, Nonoyama S, Durandy A, Meffre E. Cantaert T, et al. Among authors: schickel jn. Immunity. 2015 Nov 17;43(5):884-95. doi: 10.1016/j.immuni.2015.10.002. Epub 2015 Nov 3. Immunity. 2015. PMID: 26546282 Free PMC article.
Decreased somatic hypermutation induces an impaired peripheral B cell tolerance checkpoint.
Cantaert T, Schickel JN, Bannock JM, Ng YS, Massad C, Delmotte FR, Yamakawa N, Glauzy S, Chamberlain N, Kinnunen T, Menard L, Lavoie A, Walter JE, Notarangelo LD, Bruneau J, Al-Herz W, Kilic SS, Ochs HD, Cunningham-Rundles C, van der Burg M, Kuijpers TW, Kracker S, Kaneko H, Sekinaka Y, Nonoyama S, Durandy A, Meffre E. Cantaert T, et al. Among authors: schickel jn. J Clin Invest. 2016 Nov 1;126(11):4289-4302. doi: 10.1172/JCI84645. Epub 2016 Oct 4. J Clin Invest. 2016. PMID: 27701145 Free PMC article.
PTPN22 inhibition resets defective human central B cell tolerance.
Schickel JN, Kuhny M, Baldo A, Bannock JM, Massad C, Wang H, Katz N, Oe T, Menard L, Soulas-Sprauel P, Strowig T, Flavell R, Meffre E. Schickel JN, et al. Sci Immunol. 2016;1(1):aaf7153. doi: 10.1126/sciimmunol.aaf7153. Epub 2016 Jul 22. Sci Immunol. 2016. PMID: 27917411 Free PMC article.
Self-reactive VH4-34-expressing IgG B cells recognize commensal bacteria.
Schickel JN, Glauzy S, Ng YS, Chamberlain N, Massad C, Isnardi I, Katz N, Uzel G, Holland SM, Picard C, Puel A, Casanova JL, Meffre E. Schickel JN, et al. J Exp Med. 2017 Jul 3;214(7):1991-2003. doi: 10.1084/jem.20160201. Epub 2017 May 12. J Exp Med. 2017. PMID: 28500047 Free PMC article.
28 results