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Sialic acids in pancreatic cancer cells drive tumour-associated macrophage differentiation via the Siglec receptors Siglec-7 and Siglec-9.
Rodriguez E, Boelaars K, Brown K, Eveline Li RJ, Kruijssen L, Bruijns SCM, van Ee T, Schetters STT, Crommentuijn MHW, van der Horst JC, van Grieken NCT, van Vliet SJ, Kazemier G, Giovannetti E, Garcia-Vallejo JJ, van Kooyk Y. Rodriguez E, et al. Among authors: schetters stt. Nat Commun. 2021 Feb 24;12(1):1270. doi: 10.1038/s41467-021-21550-4. Nat Commun. 2021. PMID: 33627655 Free PMC article.
Sialic acid-modified antigens impose tolerance via inhibition of T-cell proliferation and de novo induction of regulatory T cells.
Perdicchio M, Ilarregui JM, Verstege MI, Cornelissen LA, Schetters ST, Engels S, Ambrosini M, Kalay H, Veninga H, den Haan JM, van Berkel LA, Samsom JN, Crocker PR, Sparwasser T, Berod L, Garcia-Vallejo JJ, van Kooyk Y, Unger WW. Perdicchio M, et al. Proc Natl Acad Sci U S A. 2016 Mar 22;113(12):3329-34. doi: 10.1073/pnas.1507706113. Epub 2016 Mar 3. Proc Natl Acad Sci U S A. 2016. PMID: 26941238 Free PMC article.
Neuroinflammation: Microglia and T Cells Get Ready to Tango.
Schetters STT, Gomez-Nicola D, Garcia-Vallejo JJ, Van Kooyk Y. Schetters STT, et al. Front Immunol. 2018 Jan 25;8:1905. doi: 10.3389/fimmu.2017.01905. eCollection 2017. Front Immunol. 2018. PMID: 29422891 Free PMC article.
Functional CD169 on Macrophages Mediates Interaction with Dendritic Cells for CD8+ T Cell Cross-Priming.
van Dinther D, Veninga H, Iborra S, Borg EGF, Hoogterp L, Olesek K, Beijer MR, Schetters STT, Kalay H, Garcia-Vallejo JJ, Franken KL, Cham LB, Lang KS, van Kooyk Y, Sancho D, Crocker PR, den Haan JMM. van Dinther D, et al. Among authors: schetters stt. Cell Rep. 2018 Feb 6;22(6):1484-1495. doi: 10.1016/j.celrep.2018.01.021. Cell Rep. 2018. PMID: 29425504 Free article.
Mouse DC-SIGN/CD209a as Target for Antigen Delivery and Adaptive Immunity.
Schetters STT, Kruijssen LJW, Crommentuijn MHW, Kalay H, Ochando J, den Haan JMM, Garcia-Vallejo JJ, van Kooyk Y. Schetters STT, et al. Front Immunol. 2018 May 7;9:990. doi: 10.3389/fimmu.2018.00990. eCollection 2018. Front Immunol. 2018. PMID: 29867967 Free PMC article.
Outer membrane vesicles engineered to express membrane-bound antigen program dendritic cells for cross-presentation to CD8+ T cells.
Schetters STT, Jong WSP, Horrevorts SK, Kruijssen LJW, Engels S, Stolk D, Daleke-Schermerhorn MH, Garcia-Vallejo J, Houben D, Unger WWJ, den Haan JMM, Luirink J, van Kooyk Y. Schetters STT, et al. Acta Biomater. 2019 Jun;91:248-257. doi: 10.1016/j.actbio.2019.04.033. Epub 2019 Apr 17. Acta Biomater. 2019. PMID: 31003032 Free article.
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