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Targeting virulence regulation to disarm Acinetobacter baumannii pathogenesis.
Trebosc V, Lucchini V, Narwal M, Wicki B, Gartenmann S, Schellhorn B, Schill J, Bourotte M, Frey D, Grünberg J, Trauner A, Ferrari L, Felici A, Champion OL, Gitzinger M, Lociuro S, Kammerer RA, Kemmer C, Pieren M. Trebosc V, et al. Among authors: schellhorn b. Virulence. 2022 Dec;13(1):1868-1883. doi: 10.1080/21505594.2022.2135273. Virulence. 2022. PMID: 36261919 Free PMC article.
A Novel Genome-Editing Platform for Drug-Resistant Acinetobacter baumannii Reveals an AdeR-Unrelated Tigecycline Resistance Mechanism.
Trebosc V, Gartenmann S, Royet K, Manfredi P, Tötzl M, Schellhorn B, Pieren M, Tigges M, Lociuro S, Sennhenn PC, Gitzinger M, Bumann D, Kemmer C. Trebosc V, et al. Among authors: schellhorn b. Antimicrob Agents Chemother. 2016 Nov 21;60(12):7263-7271. doi: 10.1128/AAC.01275-16. Print 2016 Dec. Antimicrob Agents Chemother. 2016. PMID: 27671072 Free PMC article.
Chemical Validation of DegS As a Target for the Development of Antibiotics with a Novel Mode of Action.
Bongard J, Schmitz AL, Wolf A, Zischinsky G, Pieren M, Schellhorn B, Bravo-Rodriguez K, Schillinger J, Koch U, Nussbaumer P, Klebl B, Steinmann J, Buer J, Sanchez-Garcia E, Ehrmann M, Kaiser M. Bongard J, et al. Among authors: schellhorn b. ChemMedChem. 2019 Jun 5;14(11):1074-1078. doi: 10.1002/cmdc.201900193. Epub 2019 Apr 24. ChemMedChem. 2019. PMID: 30945468
In vitro activity of rifabutin against 293 contemporary carbapenem-resistant Acinetobacter baumannii clinical isolates and characterization of rifabutin mode of action and resistance mechanisms.
Trebosc V, Schellhorn B, Schill J, Lucchini V, Bühler J, Bourotte M, Butcher JJ, Gitzinger M, Lociuro S, Kemmer C, Dale GE. Trebosc V, et al. Among authors: schellhorn b. J Antimicrob Chemother. 2020 Dec 1;75(12):3552-3562. doi: 10.1093/jac/dkaa370. J Antimicrob Chemother. 2020. PMID: 32869081 Free PMC article.
Structure-activity relationships of actively FhuE transported rifabutin derivatives with potent activity against Acinetobacter baumannii.
Maingot M, Bourotte M, Vetter AC, Schellhorn B, Antraygues K, Scherer H, Gitzinger M, Kemmer C, Dale GE, Defert O, Lociuro S, Brönstrup M, Willand N, Trebosc V. Maingot M, et al. Among authors: schellhorn b. Eur J Med Chem. 2023 Apr 5;252:115257. doi: 10.1016/j.ejmech.2023.115257. Epub 2023 Mar 16. Eur J Med Chem. 2023. PMID: 36948128