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Cell-type-restricted anti-cytokine therapy: TNF inhibition from one pathogenic source.
Efimov GA, Kruglov AA, Khlopchatnikova ZV, Rozov FN, Mokhonov VV, Rose-John S, Scheller J, Gordon S, Stacey M, Drutskaya MS, Tillib SV, Nedospasov SA. Efimov GA, et al. Among authors: scheller j. Proc Natl Acad Sci U S A. 2016 Mar 15;113(11):3006-11. doi: 10.1073/pnas.1520175113. Epub 2016 Mar 2. Proc Natl Acad Sci U S A. 2016. PMID: 26936954 Free PMC article.
No inhibition of IL-27 signaling by soluble gp130.
Scheller J, Schuster B, Hölscher C, Yoshimoto T, Rose-John S. Scheller J, et al. Biochem Biophys Res Commun. 2005 Jan 28;326(4):724-8. doi: 10.1016/j.bbrc.2004.11.098. Biochem Biophys Res Commun. 2005. PMID: 15607729
Forced dimerization of gp130 leads to constitutive STAT3 activation, cytokine-independent growth, and blockade of differentiation of embryonic stem cells.
Stuhlmann-Laeisz C, Lang S, Chalaris A, Krzysztof P, Enge S, Eichler J, Klingmüller U, Samuel M, Ernst M, Rose-John S, Scheller J. Stuhlmann-Laeisz C, et al. Among authors: scheller j. Mol Biol Cell. 2006 Jul;17(7):2986-95. doi: 10.1091/mbc.e05-12-1129. Epub 2006 Apr 19. Mol Biol Cell. 2006. PMID: 16624864 Free PMC article.
Interleukin-6 and its receptor: from bench to bedside.
Scheller J, Rose-John S. Scheller J, et al. Med Microbiol Immunol. 2006 Dec;195(4):173-83. doi: 10.1007/s00430-006-0019-9. Epub 2006 May 31. Med Microbiol Immunol. 2006. PMID: 16741736 Review.
236 results