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Tumor-Infiltrating Lymphocyte Therapy or Ipilimumab in Advanced Melanoma.
Rohaan MW, Borch TH, van den Berg JH, Met Ö, Kessels R, Geukes Foppen MH, Stoltenborg Granhøj J, Nuijen B, Nijenhuis C, Jedema I, van Zon M, Scheij S, Beijnen JH, Hansen M, Voermans C, Noringriis IM, Monberg TJ, Holmstroem RB, Wever LDV, van Dijk M, Grijpink-Ongering LG, Valkenet LHM, Torres Acosta A, Karger M, Borgers JSW, Ten Ham RMT, Retèl VP, van Harten WH, Lalezari F, van Tinteren H, van der Veldt AAM, Hospers GAP, Stevense-den Boer MAM, Suijkerbuijk KPM, Aarts MJB, Piersma D, van den Eertwegh AJM, de Groot JB, Vreugdenhil G, Kapiteijn E, Boers-Sonderen MJ, Fiets WE, van den Berkmortel FWPJ, Ellebaek E, Hölmich LR, van Akkooi ACJ, van Houdt WJ, Wouters MWJM, van Thienen JV, Blank CU, Meerveld-Eggink A, Klobuch S, Wilgenhof S, Schumacher TN, Donia M, Svane IM, Haanen JBAG. Rohaan MW, et al. Among authors: scheij s. N Engl J Med. 2022 Dec 8;387(23):2113-2125. doi: 10.1056/NEJMoa2210233. N Engl J Med. 2022. PMID: 36477031 Clinical Trial.
MART-1 TCR gene-modified peripheral blood T cells for the treatment of metastatic melanoma: a phase I/IIa clinical trial.
Rohaan MW, Gomez-Eerland R, van den Berg JH, Geukes Foppen MH, van Zon M, Raud B, Jedema I, Scheij S, de Boer R, Bakker NAM, van den Broek D, Pronk LM, Grijpink-Ongering LG, Sari A, Kessels R, van den Haak M, Mallo HA, Karger M, van de Wiel BA, Zuur CL, Duinkerken CW, Lalezari F, van Thienen JV, Wilgenhof S, Blank CU, Beijnen JH, Nuijen B, Schumacher TN, Haanen JBAG. Rohaan MW, et al. Among authors: scheij s. Immunooncol Technol. 2022 Jun 18;15:100089. doi: 10.1016/j.iotech.2022.100089. eCollection 2022 Sep. Immunooncol Technol. 2022. PMID: 35865122 Free PMC article.
Regulation of intestinal LDLR by the LXR-IDOL axis.
van Loon NM, van Wouw SAE, Ottenhoff R, Nelson JK, Kingma J, Scheij S, Moeton M, Zelcer N. van Loon NM, et al. Among authors: scheij s. Atherosclerosis. 2020 Dec;315:1-9. doi: 10.1016/j.atherosclerosis.2020.10.898. Epub 2020 Nov 9. Atherosclerosis. 2020. PMID: 33190106 Free article.
Haploid genetic screens identify SPRING/C12ORF49 as a determinant of SREBP signaling and cholesterol metabolism.
Loregger A, Raaben M, Nieuwenhuis J, Tan JME, Jae LT, van den Hengel LG, Hendrix S, van den Berg M, Scheij S, Song JY, Huijbers IJ, Kroese LJ, Ottenhoff R, van Weeghel M, van de Sluis B, Brummelkamp T, Zelcer N. Loregger A, et al. Among authors: scheij s. Nat Commun. 2020 Feb 28;11(1):1128. doi: 10.1038/s41467-020-14811-1. Nat Commun. 2020. PMID: 32111832 Free PMC article.
The Iminosugar AMP-DNM Improves Satiety and Activates Brown Adipose Tissue Through GLP1.
Herrera Moro Chao D, Wang Y, Foppen E, Ottenhoff R, van Roomen C, Parlevliet ET, van Eijk M, Verhoek M, Boot R, Marques AR, Scheij S, Mirzaian M, Kooijman S, Jansen K, Wang D, Mergen C, Seeley RJ, Tschöp MH, Overkleeft H, Rensen PCN, Kalsbeek A, Aerts JMFG, Yi CX. Herrera Moro Chao D, et al. Among authors: scheij s. Diabetes. 2019 Dec;68(12):2223-2234. doi: 10.2337/db19-0049. Epub 2019 Oct 2. Diabetes. 2019. PMID: 31578192
Inactivation of the E3 Ubiquitin Ligase IDOL Attenuates Diet-Induced Obesity and Metabolic Dysfunction in Mice.
van Loon NM, Ottenhoff R, Kooijman S, Moeton M, Scheij S, Roscam Abbing RLP, Gijbels MJJ, Levels JHM, Sorrentino V, Berbée JFP, Rensen PCN, Zelcer N. van Loon NM, et al. Among authors: scheij s. Arterioscler Thromb Vasc Biol. 2018 Aug;38(8):1785-1795. doi: 10.1161/ATVBAHA.118.311168. Arterioscler Thromb Vasc Biol. 2018. PMID: 29903737 Free PMC article.
Haploid Mammalian Genetic Screen Identifies UBXD8 as a Key Determinant of HMGCR Degradation and Cholesterol Biosynthesis.
Loregger A, Raaben M, Tan J, Scheij S, Moeton M, van den Berg M, Gelberg-Etel H, Stickel E, Roitelman J, Brummelkamp T, Zelcer N. Loregger A, et al. Among authors: scheij s. Arterioscler Thromb Vasc Biol. 2017 Nov;37(11):2064-2074. doi: 10.1161/ATVBAHA.117.310002. Epub 2017 Sep 7. Arterioscler Thromb Vasc Biol. 2017. PMID: 28882874 Free PMC article.
Stabilization of Glucocerebrosidase by Active Site Occupancy.
Ben Bdira F, Kallemeijn WW, Oussoren SV, Scheij S, Bleijlevens B, Florea BI, van Roomen CPAA, Ottenhoff R, van Kooten MJFM, Walvoort MTC, Witte MD, Boot RG, Ubbink M, Overkleeft HS, Aerts JMFG. Ben Bdira F, et al. Among authors: scheij s. ACS Chem Biol. 2017 Jul 21;12(7):1830-1841. doi: 10.1021/acschembio.7b00276. Epub 2017 May 22. ACS Chem Biol. 2017. PMID: 28485919 Free PMC article.
38 results