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An In Vivo CRISPR Screening Platform for Prioritizing Therapeutic Targets in AML.
Cancer Discov. 2022 Feb;12(2):432-449. doi: 10.1158/2159-8290.CD-20-1851. Epub 2021 Sep 16.
Cancer Discov. 2022.
PMID: 34531254
Free PMC article.
Mitochondrial fusion is a therapeutic vulnerability of acute myeloid leukemia.
Larrue C, Mouche S, Lin S, Simonetta F, Scheidegger NK, Poulain L, Birsen R, Sarry JE, Stegmaier K, Tamburini J.
Larrue C, et al. Among authors: scheidegger nk.
Leukemia. 2023 Apr;37(4):765-775. doi: 10.1038/s41375-023-01835-x. Epub 2023 Feb 4.
Leukemia. 2023.
PMID: 36739349
Free PMC article.
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Xenografts of highly resistant leukemia recapitulate the clonal composition of the leukemogenic compartment.
Schmitz M, Breithaupt P, Scheidegger N, Cario G, Bonapace L, Meissner B, Mirkowska P, Tchinda J, Niggli FK, Stanulla M, Schrappe M, Schrauder A, Bornhauser BC, Bourquin JP.
Schmitz M, et al.
Blood. 2011 Aug 18;118(7):1854-64. doi: 10.1182/blood-2010-11-320309. Epub 2011 Jun 13.
Blood. 2011.
PMID: 21670474
Free article.
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The hematopoietic stem cell marker VNN2 is associated with chemoresistance in pediatric B-cell precursor ALL.
Bornhauser B, Cario G, Rinaldi A, Risch T, Rodriguez Martinez V, Schütte M, Warnatz HJ, Scheidegger N, Mirkowska P, Temperli M, Möller C, Schumich A, Dworzak M, Attarbaschi A, Brüggemann M, Ritgen M, Mejstrikova E, Hofmann A, Buldini B, Scarparo P, Basso G, Maglia O, Gaipa G, Skoblyn TL, Te Kronnie G, Vendramini E, Panzer-Grümayer R, Barz MJ, Marovca B, Hauri-Hohl M, Niggli F, Eckert C, Schrappe M, Stanulla M, Zimmermann M, Wollscheid B, Yaspo ML, Bourquin JP.
Bornhauser B, et al.
Blood Adv. 2020 Sep 8;4(17):4052-4064. doi: 10.1182/bloodadvances.2019000938.
Blood Adv. 2020.
PMID: 32853382
Free PMC article.
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