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LAMTOR/Ragulator is a negative regulator of Arl8b- and BORC-dependent late endosomal positioning.
Filipek PA, de Araujo MEG, Vogel GF, De Smet CH, Eberharter D, Rebsamen M, Rudashevskaya EL, Kremser L, Yordanov T, Tschaikner P, Fürnrohr BG, Lechner S, Dunzendorfer-Matt T, Scheffzek K, Bennett KL, Superti-Furga G, Lindner HH, Stasyk T, Huber LA. Filipek PA, et al. Among authors: scheffzek k. J Cell Biol. 2017 Dec 4;216(12):4199-4215. doi: 10.1083/jcb.201703061. Epub 2017 Oct 9. J Cell Biol. 2017. PMID: 28993467 Free PMC article.
Crystal structure of the human lysosomal mTORC1 scaffold complex and its impact on signaling.
de Araujo MEG, Naschberger A, Fürnrohr BG, Stasyk T, Dunzendorfer-Matt T, Lechner S, Welti S, Kremser L, Shivalingaiah G, Offterdinger M, Lindner HH, Huber LA, Scheffzek K. de Araujo MEG, et al. Among authors: scheffzek k. Science. 2017 Oct 20;358(6361):377-381. doi: 10.1126/science.aao1583. Epub 2017 Sep 21. Science. 2017. PMID: 28935770
Structural basis of activation of the tumor suppressor protein neurofibromin.
Chaker-Margot M, Werten S, Dunzendorfer-Matt T, Lechner S, Ruepp A, Scheffzek K, Maier T. Chaker-Margot M, et al. Among authors: scheffzek k. Mol Cell. 2022 Apr 7;82(7):1288-1296.e5. doi: 10.1016/j.molcel.2022.03.011. Epub 2022 Mar 29. Mol Cell. 2022. PMID: 35353986 Free article.
Cleaning protocols for crystallization robots: preventing protease contamination.
Naschberger A, Fürnrohr BG, Dunzendorfer-Matt T, Bonagura CA, Wright D, Scheffzek K, Rupp B. Naschberger A, et al. Among authors: scheffzek k. Acta Crystallogr F Struct Biol Commun. 2015 Jan 1;71(Pt 1):100-2. doi: 10.1107/S2053230X14026053. Epub 2015 Jan 1. Acta Crystallogr F Struct Biol Commun. 2015. PMID: 25615978 Free PMC article.
Structural basis for the autoinhibition of c-Abl tyrosine kinase.
Nagar B, Hantschel O, Young MA, Scheffzek K, Veach D, Bornmann W, Clarkson B, Superti-Furga G, Kuriyan J. Nagar B, et al. Among authors: scheffzek k. Cell. 2003 Mar 21;112(6):859-71. doi: 10.1016/s0092-8674(03)00194-6. Cell. 2003. PMID: 12654251 Free article.
The N14 anti-afamin antibody Fab: a rare VL1 CDR glycosylation, crystallographic re-sequencing, molecular plasticity and conservative versus enthusiastic modelling.
Naschberger A, Fürnrohr BG, Lenac Rovis T, Malic S, Scheffzek K, Dieplinger H, Rupp B. Naschberger A, et al. Among authors: scheffzek k. Acta Crystallogr D Struct Biol. 2016 Dec 1;72(Pt 12):1267-1280. doi: 10.1107/S205979831601723X. Epub 2016 Nov 29. Acta Crystallogr D Struct Biol. 2016. PMID: 27917827 Free PMC article.
Expression, Purification, and Biochemical Characterization of Human Afamin.
Altamirano A, Naschberger A, Fürnrohr BG, Saldova R, Struwe WB, Jennings PM, Millán Martín S, Malic S, Plangger I, Lechner S, Pisano R, Peretti N, Linke B, Aguiar MM, Fresser F, Ritsch A, Lenac Rovis T, Goode C, Rudd PM, Scheffzek K, Rupp B, Dieplinger H. Altamirano A, et al. Among authors: scheffzek k. J Proteome Res. 2018 Mar 2;17(3):1269-1277. doi: 10.1021/acs.jproteome.7b00867. Epub 2018 Feb 20. J Proteome Res. 2018. PMID: 29441788
Structural basis for the bi-functionality of human oxaloacetate decarboxylase FAHD1.
Weiss AKH, Naschberger A, Loeffler JR, Gstach H, Bowler MW, Holzknecht M, Cappuccio E, Pittl A, Etemad S, Dunzendorfer-Matt T, Scheffzek K, Liedl KR, Jansen-Dürr P. Weiss AKH, et al. Among authors: scheffzek k. Biochem J. 2018 Nov 20;475(22):3561-3576. doi: 10.1042/BCJ20180750. Biochem J. 2018. PMID: 30348641 Free PMC article.
85 results