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The Highly Potent AhR Agonist Picoberin Modulates Hh-Dependent Osteoblast Differentiation.
Flegel J, Shaaban S, Jia ZJ, Schulte B, Lian Y, Krzyzanowski A, Metz M, Schneidewind T, Wesseler F, Flegel A, Reich A, Brause A, Xue G, Zhang M, Dötsch L, Stender ID, Hoffmann JE, Scheel R, Janning P, Rastinejad F, Schade D, Strohmann C, Antonchick AP, Sievers S, Moura-Alves P, Ziegler S, Waldmann H. Flegel J, et al. Among authors: scheel r. J Med Chem. 2022 Dec 22;65(24):16268-16289. doi: 10.1021/acs.jmedchem.2c00956. Epub 2022 Dec 2. J Med Chem. 2022. PMID: 36459434 Free PMC article.
Synthesis and crystal structure of [Zn6Br4(C9H18NO)4(OH)4]·2C3H6O2.
Scheel R, Brieger L, Louven K, Strohmann C. Scheel R, et al. Acta Crystallogr E Crystallogr Commun. 2020 Jun 2;76(Pt 7):998-1002. doi: 10.1107/S2056989020007100. eCollection 2020 Jul 1. Acta Crystallogr E Crystallogr Commun. 2020. PMID: 32695440 Free PMC article.
Natural product fragment combination to performance-diverse pseudo-natural products.
Grigalunas M, Burhop A, Zinken S, Pahl A, Gally JM, Wild N, Mantel Y, Sievers S, Foley DJ, Scheel R, Strohmann C, Antonchick AP, Waldmann H. Grigalunas M, et al. Among authors: scheel r. Nat Commun. 2021 Mar 25;12(1):1883. doi: 10.1038/s41467-021-22174-4. Nat Commun. 2021. PMID: 33767198 Free PMC article.
Identification of a Novel Pseudo-Natural Product Type IV IDO1 Inhibitor Chemotype.
Davies C, Dötsch L, Ciulla MG, Hennes E, Yoshida K, Gasper R, Scheel R, Sievers S, Strohmann C, Kumar K, Ziegler S, Waldmann H. Davies C, et al. Among authors: scheel r. Angew Chem Int Ed Engl. 2022 Oct 4;61(40):e202209374. doi: 10.1002/anie.202209374. Epub 2022 Aug 29. Angew Chem Int Ed Engl. 2022. PMID: 35959923 Free PMC article.
Collective Synthesis of Sarpagine and Macroline Alkaloid-Inspired Compounds.
Aoyama H, Davies C, Liu J, Pahl A, Kirchhoff JL, Scheel R, Sievers S, Strohmann C, Grigalunas M, Waldmann H. Aoyama H, et al. Among authors: scheel r. Chemistry. 2024 Jan 22;30(5):e202303027. doi: 10.1002/chem.202303027. Epub 2023 Nov 29. Chemistry. 2024. PMID: 37755456
39 results