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Structural analysis of TrkA mutations in patients with congenital insensitivity to pain reveals PLCγ as an analgesic drug target.
Moraes BC, Ribeiro-Filho HV, Roldão AP, Toniolo EF, Carretero GPB, Sgro GG, Batista FAH, Berardi DE, Oliveira VRS, Tomasin R, Vieceli FM, Pramio DT, Cardoso AB, Figueira ACM, Farah SC, Devi LA, Dale CS, de Oliveira PSL, Schechtman D. Moraes BC, et al. Among authors: schechtman d. Sci Signal. 2022 Apr 26;15(731):eabm6046. doi: 10.1126/scisignal.abm6046. Epub 2022 Apr 26. Sci Signal. 2022. PMID: 35471943
Phosphoproteomics profiling suggests a role for nuclear βΙPKC in transcription processes of undifferentiated murine embryonic stem cells.
Costa-Junior HM, Garavello NM, Duarte ML, Berti DA, Glaser T, de Andrade A, Labate CA, Ferreira AT, Perales JE, Xavier-Neto J, Krieger JE, Schechtman D. Costa-Junior HM, et al. Among authors: schechtman d. J Proteome Res. 2010 Dec 3;9(12):6191-206. doi: 10.1021/pr100355k. Epub 2010 Nov 1. J Proteome Res. 2010. PMID: 20936827
Scaffold proteins LACK and TRACK as potential drug targets in kinetoplastid parasites: Development of inhibitors.
Qvit N, Schechtman D, Pena DA, Berti DA, Soares CO, Miao Q, Liang LA, Baron LA, Teh-Poot C, Martínez-Vega P, Ramirez-Sierra MJ, Churchill E, Cunningham AD, Malkovskiy AV, Federspiel NA, Gozzo FC, Torrecilhas AC, Manso Alves MJ, Jardim A, Momar N, Dumonteil E, Mochly-Rosen D. Qvit N, et al. Among authors: schechtman d. Int J Parasitol Drugs Drug Resist. 2016 Feb 12;6(1):74-84. doi: 10.1016/j.ijpddr.2016.02.003. eCollection 2016 Apr. Int J Parasitol Drugs Drug Resist. 2016. PMID: 27054066 Free PMC article.
68 results