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VEGF-C-expressing TAMs rewire the metastatic fate of breast cancer cells.
Banerjee K, Kerzel T, Bekkhus T, de Souza Ferreira S, Wallmann T, Wallerius M, Landwehr LS, Agardy DA, Schauer N, Malmerfeldt A, Bergh J, Bartish M, Hartman J, Östman A, Squadrito ML, Rolny C. Banerjee K, et al. Among authors: schauer n. Cell Rep. 2023 Dec 26;42(12):113507. doi: 10.1016/j.celrep.2023.113507. Epub 2023 Dec 1. Cell Rep. 2023. PMID: 38041815 Free article.
Accelerating inhibitor discovery for deubiquitinating enzymes.
Chan WC, Liu X, Magin RS, Girardi NM, Ficarro SB, Hu W, Tarazona Guzman MI, Starnbach CA, Felix A, Adelmant G, Varca AC, Hu B, Bratt AS, DaSilva E, Schauer NJ, Jaen Maisonet I, Dolen EK, Ayala AX, Marto JA, Buhrlage SJ. Chan WC, et al. Among authors: schauer nj. Nat Commun. 2023 Feb 8;14(1):686. doi: 10.1038/s41467-023-36246-0. Nat Commun. 2023. PMID: 36754960 Free PMC article.
Small molecule inhibition of deubiquitinating enzyme JOSD1 as a novel targeted therapy for leukemias with mutant JAK2.
Yang J, Weisberg EL, Liu X, Magin RS, Chan WC, Hu B, Schauer NJ, Zhang S, Lamberto I, Doherty L, Meng C, Sattler M, Cabal-Hierro L, Winer E, Stone R, Marto JA, Griffin JD, Buhrlage SJ. Yang J, et al. Among authors: schauer nj. Leukemia. 2022 Jan;36(1):210-220. doi: 10.1038/s41375-021-01336-9. Epub 2021 Jul 29. Leukemia. 2022. PMID: 34326465
Proteomics-Based Identification of DUB Substrates Using Selective Inhibitors.
Bushman JW, Donovan KA, Schauer NJ, Liu X, Hu W, Varca AC, Buhrlage SJ, Fischer ES. Bushman JW, et al. Among authors: schauer nj. Cell Chem Biol. 2021 Jan 21;28(1):78-87.e3. doi: 10.1016/j.chembiol.2020.09.005. Epub 2020 Oct 1. Cell Chem Biol. 2021. PMID: 33007217 Free PMC article.
Selective USP7 inhibition elicits cancer cell killing through a p53-dependent mechanism.
Schauer NJ, Liu X, Magin RS, Doherty LM, Chan WC, Ficarro SB, Hu W, Roberts RM, Iacob RE, Stolte B, Giacomelli AO, Perera S, McKay K, Boswell SA, Weisberg EL, Ray A, Chauhan D, Dhe-Paganon S, Anderson KC, Griffin JD, Li J, Hahn WC, Sorger PK, Engen JR, Stegmaier K, Marto JA, Buhrlage SJ. Schauer NJ, et al. Sci Rep. 2020 Mar 24;10(1):5324. doi: 10.1038/s41598-020-62076-x. Sci Rep. 2020. PMID: 32210275 Free PMC article.
Deubiquitinases Maintain Protein Homeostasis and Survival of Cancer Cells upon Glutathione Depletion.
Harris IS, Endress JE, Coloff JL, Selfors LM, McBrayer SK, Rosenbluth JM, Takahashi N, Dhakal S, Koduri V, Oser MG, Schauer NJ, Doherty LM, Hong AL, Kang YP, Younger ST, Doench JG, Hahn WC, Buhrlage SJ, DeNicola GM, Kaelin WG Jr, Brugge JS. Harris IS, et al. Among authors: schauer nj. Cell Metab. 2019 May 7;29(5):1166-1181.e6. doi: 10.1016/j.cmet.2019.01.020. Epub 2019 Feb 21. Cell Metab. 2019. PMID: 30799286 Free PMC article.
79 results