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A Kelch13-defined endocytosis pathway mediates artemisinin resistance in malaria parasites.
Birnbaum J, Scharf S, Schmidt S, Jonscher E, Hoeijmakers WAM, Flemming S, Toenhake CG, Schmitt M, Sabitzki R, Bergmann B, Fröhlke U, Mesén-Ramírez P, Blancke Soares A, Herrmann H, Bártfai R, Spielmann T. Birnbaum J, et al. Among authors: scharf s. Science. 2020 Jan 3;367(6473):51-59. doi: 10.1126/science.aax4735. Science. 2020. PMID: 31896710
Identification of novel inner membrane complex and apical annuli proteins of the malaria parasite Plasmodium falciparum.
Wichers JS, Wunderlich J, Heincke D, Pazicky S, Strauss J, Schmitt M, Kimmel J, Wilcke L, Scharf S, von Thien H, Burda PC, Spielmann T, Löw C, Filarsky M, Bachmann A, Gilberger TW. Wichers JS, et al. Among authors: scharf s. Cell Microbiol. 2021 Sep;23(9):e13341. doi: 10.1111/cmi.13341. Epub 2021 May 16. Cell Microbiol. 2021. PMID: 33830607
A novel antibiotic class targeting the lipopolysaccharide transporter.
Zampaloni C, Mattei P, Bleicher K, Winther L, Thäte C, Bucher C, Adam JM, Alanine A, Amrein KE, Baidin V, Bieniossek C, Bissantz C, Boess F, Cantrill C, Clairfeuille T, Dey F, Di Giorgio P, du Castel P, Dylus D, Dzygiel P, Felici A, García-Alcalde F, Haldimann A, Leipner M, Leyn S, Louvel S, Misson P, Osterman A, Pahil K, Rigo S, Schäublin A, Scharf S, Schmitz P, Stoll T, Trauner A, Zoffmann S, Kahne D, Young JAT, Lobritz MA, Bradley KA. Zampaloni C, et al. Among authors: scharf s. Nature. 2024 Jan;625(7995):566-571. doi: 10.1038/s41586-023-06873-0. Epub 2024 Jan 3. Nature. 2024. PMID: 38172634 Free PMC article.
Postpartum cryptococcosis in an HIV-negative patient.
Gottschling M, Blaas S, Geismann F, Lerzer C, Malfertheiner M, Salzberger B, Hitzenbichler F, Scharf S, Weber F, Mohr A. Gottschling M, et al. Among authors: scharf s. Infection. 2024 Apr;52(2):691-696. doi: 10.1007/s15010-023-02151-3. Epub 2023 Dec 19. Infection. 2024. PMID: 38113019
524 results