Schaner Tooley CE - Search Results

1

Novel regulation of the transcription factor ZHX2 by N-terminal methylation.

Conner MM, Parker HV, Falcone DR, Chung G, Schaner Tooley CE. Conner MM, et al. Among authors: schaner tooley ce. Transcription. 2022 Feb-Jun;13(1-3):1-15. doi: 10.1080/21541264.2022.2079184. Epub 2022 May 25. Transcription. 2022. PMID: 35613330 Free PMC article.

2

The N-terminal methyltransferase homologs NRMT1 and NRMT2 exhibit novel regulation of activity through heterotrimer formation.

Faughn JD, Dean WL, Schaner Tooley CE. Faughn JD, et al. Among authors: schaner tooley ce. Protein Sci. 2018 Sep;27(9):1585-1599. doi: 10.1002/pro.3456. Epub 2018 Sep 24. Protein Sci. 2018. PMID: 30151928 Free PMC article.

3

Selective Peptidomimetic Inhibitors of NTMT1/2: Rational Design, Synthesis, Characterization, and Crystallographic Studies.

Mackie BD, Chen D, Dong G, Dong C, Parker H, Schaner Tooley CE, Noinaj N, Min J, Huang R. Mackie BD, et al. Among authors: schaner tooley ce. J Med Chem. 2020 Sep 10;63(17):9512-9522. doi: 10.1021/acs.jmedchem.0c00689. Epub 2020 Aug 5. J Med Chem. 2020. PMID: 32689795 Free PMC article.

4

CREB-mediated transcriptional activation of NRMT1 drives muscle differentiation.

Tooley JG, Catlin JP, Schaner Tooley CE. Tooley JG, et al. Among authors: schaner tooley ce. Transcription. 2021 Apr-Jun;12(2-3):72-88. doi: 10.1080/21541264.2021.1963627. Epub 2021 Aug 17. Transcription. 2021. PMID: 34403304 Free PMC article.

5

Three's a crowd - why did three N-terminal methyltransferases evolve for one job?

Conner MM, Schaner Tooley CE. Conner MM, et al. Among authors: schaner tooley ce. J Cell Sci. 2023 Jan 15;136(2):jcs260424. doi: 10.1242/jcs.260424. Epub 2023 Jan 17. J Cell Sci. 2023. PMID: 36647772 Free PMC article.

6

Optimizing purification and activity assays of N-terminal methyltransferase complexes.

Parker HV, Tooley JG, Schaner Tooley CE. Parker HV, et al. Among authors: schaner tooley ce. Methods Enzymol. 2023;684:71-111. doi: 10.1016/bs.mie.2023.02.001. Epub 2023 Mar 6. Methods Enzymol. 2023. PMID: 37230594 Free PMC article.

7

Select human cancer mutants of NRMT1 alter its catalytic activity and decrease N-terminal trimethylation.

Shields KM, Tooley JG, Petkowski JJ, Wilkey DW, Garbett NC, Merchant ML, Cheng A, Schaner Tooley CE. Shields KM, et al. Among authors: tooley jg, schaner tooley ce. Protein Sci. 2017 Aug;26(8):1639-1652. doi: 10.1002/pro.3202. Epub 2017 Jun 11. Protein Sci. 2017. PMID: 28556566 Free PMC article.

8

N-terminal acetylation and methylation differentially affect the function of MYL9.

Nevitt C, Tooley JG, Schaner Tooley CE. Nevitt C, et al. Among authors: tooley jg, schaner tooley ce. Biochem J. 2018 Oct 22;475(20):3201-3219. doi: 10.1042/BCJ20180638. Biochem J. 2018. PMID: 30242065 Free PMC article.

9

Catlin JP, Marziali LN, Rein B, Yan Z, Feltri ML, Schaner Tooley CE. Catlin JP, et al. Among authors: schaner tooley ce. Cell Death Dis. 2021 Oct 28;12(11):1014. doi: 10.1038/s41419-021-04316-0. Cell Death Dis. 2021. PMID: 34711807 Free PMC article.

10

NRMT2 is an N-terminal monomethylase that primes for its homologue NRMT1.

Petkowski JJ, Bonsignore LA, Tooley JG, Wilkey DW, Merchant ML, Macara IG, Schaner Tooley CE. Petkowski JJ, et al. Among authors: tooley jg, schaner tooley ce. Biochem J. 2013 Dec 15;456(3):453-62. doi: 10.1042/BJ20131163. Biochem J. 2013. PMID: 24090352 Free PMC article.

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