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Deregulated DNA ADP-ribosylation impairs telomere replication.
Wondisford AR, Lee J, Lu R, Schuller M, Groslambert J, Bhargava R, Schamus-Haynes S, Cespedes LC, Opresko PL, Pickett HA, Min J, Ahel I, O'Sullivan RJ. Wondisford AR, et al. Among authors: schamus haynes s. Nat Struct Mol Biol. 2024 May 7. doi: 10.1038/s41594-024-01279-6. Online ahead of print. Nat Struct Mol Biol. 2024. PMID: 38714889
Thymidine rescues ATR kinase inhibitor-induced deoxyuridine contamination in genomic DNA, cell death, and interferon-α/β expression.
Sugitani N, Vendetti FP, Cipriano AJ, Pandya P, Deppas JJ, Moiseeva TN, Schamus-Haynes S, Wang Y, Palmer D, Osmanbeyoglu HU, Bostwick A, Snyder NW, Gong YN, Aird KM, Delgoffe GM, Beumer JH, Bakkenist CJ. Sugitani N, et al. Among authors: schamus haynes s. Cell Rep. 2022 Sep 20;40(12):111371. doi: 10.1016/j.celrep.2022.111371. Cell Rep. 2022. PMID: 36130512 Free PMC article.