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Deregulated DNA ADP-ribosylation impairs telomere replication.
Nat Struct Mol Biol. 2024 May 7. doi: 10.1038/s41594-024-01279-6. Online ahead of print.
Nat Struct Mol Biol. 2024.
PMID: 38714889
The schedule of ATR inhibitor AZD6738 can potentiate or abolish antitumor immune responses to radiotherapy.
Vendetti FP, Pandya P, Clump DA, Schamus-Haynes S, Tavakoli M, diMayorca M, Islam NM, Chang J, Delgoffe GM, Beumer JH, Bakkenist CJ.
Vendetti FP, et al. Among authors: schamus haynes s.
JCI Insight. 2023 Feb 22;8(4):e165615. doi: 10.1172/jci.insight.165615.
JCI Insight. 2023.
PMID: 36810257
Free PMC article.
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Thymidine rescues ATR kinase inhibitor-induced deoxyuridine contamination in genomic DNA, cell death, and interferon-α/β expression.
Sugitani N, Vendetti FP, Cipriano AJ, Pandya P, Deppas JJ, Moiseeva TN, Schamus-Haynes S, Wang Y, Palmer D, Osmanbeyoglu HU, Bostwick A, Snyder NW, Gong YN, Aird KM, Delgoffe GM, Beumer JH, Bakkenist CJ.
Sugitani N, et al. Among authors: schamus haynes s.
Cell Rep. 2022 Sep 20;40(12):111371. doi: 10.1016/j.celrep.2022.111371.
Cell Rep. 2022.
PMID: 36130512
Free PMC article.
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An ATR and CHK1 kinase signaling mechanism that limits origin firing during unperturbed DNA replication.
Moiseeva TN, Yin Y, Calderon MJ, Qian C, Schamus-Haynes S, Sugitani N, Osmanbeyoglu HU, Rothenberg E, Watkins SC, Bakkenist CJ.
Moiseeva TN, et al. Among authors: schamus haynes s.
Proc Natl Acad Sci U S A. 2019 Jul 2;116(27):13374-13383. doi: 10.1073/pnas.1903418116. Epub 2019 Jun 17.
Proc Natl Acad Sci U S A. 2019.
PMID: 31209037
Free PMC article.
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