Schamel WW - Search Results

1

Noncanonical binding of Lck to CD3ε promotes TCR signaling and CAR function.

Hartl FA, Beck-Garcìa E, Woessner NM, Flachsmann LJ, Cárdenas RMV, Brandl SM, Taromi S, Fiala GJ, Morath A, Mishra P, Yousefi OS, Zimmermann J, Hoefflin N, Köhn M, Wöhrl BM, Zeiser R, Schweimer K, Günther S, Schamel WW, Minguet S. Hartl FA, et al. Among authors: schamel ww. Nat Immunol. 2020 Aug;21(8):902-913. doi: 10.1038/s41590-020-0732-3. Epub 2020 Jul 20. Nat Immunol. 2020. PMID: 32690949

2

Adenosine and cAMP are potent inhibitors of the NF-kappa B pathway downstream of immunoreceptors.

Minguet S, Huber M, Rosenkranz L, Schamel WW, Reth M, Brummer T. Minguet S, et al. Among authors: schamel ww. Eur J Immunol. 2005 Jan;35(1):31-41. doi: 10.1002/eji.200425524. Eur J Immunol. 2005. PMID: 15580656 Free article.

3

A conformation- and avidity-based proofreading mechanism for the TCR-CD3 complex.

Schamel WW, Risueño RM, Minguet S, Ortíz AR, Alarcón B. Schamel WW, et al. Trends Immunol. 2006 Apr;27(4):176-82. doi: 10.1016/j.it.2006.02.005. Epub 2006 Mar 9. Trends Immunol. 2006. PMID: 16527543

4

Blue native polyacrylamide gel electrophoresis (BN-PAGE) for the identification and analysis of multiprotein complexes.

Swamy M, Siegers GM, Minguet S, Wollscheid B, Schamel WW. Swamy M, et al. Among authors: schamel ww. Sci STKE. 2006 Jul 25;2006(345):pl4. doi: 10.1126/stke.3452006pl4. Sci STKE. 2006. PMID: 16868305

5

Full activation of the T cell receptor requires both clustering and conformational changes at CD3.

Minguet S, Swamy M, Alarcón B, Luescher IF, Schamel WW. Minguet S, et al. Among authors: schamel ww. Immunity. 2007 Jan;26(1):43-54. doi: 10.1016/j.immuni.2006.10.019. Epub 2006 Dec 21. Immunity. 2007. PMID: 17188005 Free article.

6

A native antibody-based mobility-shift technique (NAMOS-assay) to determine the stoichiometry of multiprotein complexes.

Swamy M, Minguet S, Siegers GM, Alarcón B, Schamel WW. Swamy M, et al. Among authors: schamel ww. J Immunol Methods. 2007 Jul 31;324(1-2):74-83. doi: 10.1016/j.jim.2007.05.003. Epub 2007 Jun 4. J Immunol Methods. 2007. PMID: 17568608

7

Different composition of the human and the mouse gammadelta T cell receptor explains different phenotypes of CD3gamma and CD3delta immunodeficiencies.

Siegers GM, Swamy M, Fernández-Malavé E, Minguet S, Rathmann S, Guardo AC, Pérez-Flores V, Regueiro JR, Alarcón B, Fisch P, Schamel WW. Siegers GM, et al. Among authors: schamel ww. J Exp Med. 2007 Oct 29;204(11):2537-44. doi: 10.1084/jem.20070782. Epub 2007 Oct 8. J Exp Med. 2007. PMID: 17923503 Free PMC article.

8

A permissive geometry model for TCR-CD3 activation.

Minguet S, Schamel WW. Minguet S, et al. Among authors: schamel ww. Trends Biochem Sci. 2008 Feb;33(2):51-7. doi: 10.1016/j.tibs.2007.10.008. Epub 2008 Jan 16. Trends Biochem Sci. 2008. PMID: 18201888

9

The short length of the extracellular domain of zeta is crucial for T cell antigen receptor function.

Minguet S, Swamy M, Schamel WW. Minguet S, et al. Among authors: schamel ww. Immunol Lett. 2008 Mar 15;116(2):195-202. doi: 10.1016/j.imlet.2007.11.020. Epub 2007 Dec 26. Immunol Lett. 2008. PMID: 18207249

10

The extracellular part of zeta is buried in the T cell antigen receptor complex.

Minguet S, Swamy M, Dopfer EP, Dengler E, Alarcón B, Schamel WW. Minguet S, et al. Among authors: schamel ww. Immunol Lett. 2008 Mar 15;116(2):203-10. doi: 10.1016/j.imlet.2007.11.024. Epub 2007 Dec 31. Immunol Lett. 2008. PMID: 18215426

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