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Page 1
Stroke induces disease-specific myeloid cells in the brain parenchyma and pia.
Beuker C, Schafflick D, Strecker JK, Heming M, Li X, Wolbert J, Schmidt-Pogoda A, Thomas C, Kuhlmann T, Aranda-Pardos I, A-Gonzalez N, Kumar PA, Werner Y, Kilic E, Hermann DM, Wiendl H, Stumm R, Meyer Zu Hörste G, Minnerup J. Beuker C, et al. Among authors: schafflick d. Nat Commun. 2022 Feb 17;13(1):945. doi: 10.1038/s41467-022-28593-1. Nat Commun. 2022. PMID: 35177618 Free PMC article.
Single-cell profiling of CNS border compartment leukocytes reveals that B cells and their progenitors reside in non-diseased meninges.
Schafflick D, Wolbert J, Heming M, Thomas C, Hartlehnert M, Börsch AL, Ricci A, Martín-Salamanca S, Li X, Lu IN, Pawlak M, Minnerup J, Strecker JK, Seidenbecher T, Meuth SG, Hidalgo A, Liesz A, Wiendl H, Meyer Zu Horste G. Schafflick D, et al. Nat Neurosci. 2021 Sep;24(9):1225-1234. doi: 10.1038/s41593-021-00880-y. Epub 2021 Jul 12. Nat Neurosci. 2021. PMID: 34253922
Bcl6 controls meningeal Th17-B cell interaction in murine neuroinflammation.
Hartlehnert M, Börsch AL, Li X, Burmeister M, Gerwien H, Schafflick D, Heming M, Lu IN, Narayanan V, Strecker JK, Kolz A, Peters A, Wu GF, Wiendl H, Sorokin L, Meyer Zu Horste G. Hartlehnert M, et al. Among authors: schafflick d. Proc Natl Acad Sci U S A. 2021 Sep 7;118(36):e2023174118. doi: 10.1073/pnas.2023174118. Proc Natl Acad Sci U S A. 2021. PMID: 34479995 Free PMC article.
Deterministic programming of human pluripotent stem cells into microglia facilitates studying their role in health and disease.
Speicher AM, Korn L, Csatári J, Gonzalez-Cano L, Heming M, Thomas C, Schroeter CB, Schafflick D, Li X, Gola L, Engler A, Kaehne T, Vallier L, Meuth SG, Meyer Zu Hörste G, Kovac S, Wiendl H, Schöler HR, Pawlowski M. Speicher AM, et al. Among authors: schafflick d. Proc Natl Acad Sci U S A. 2022 Oct 25;119(43):e2123476119. doi: 10.1073/pnas.2123476119. Epub 2022 Oct 17. Proc Natl Acad Sci U S A. 2022. PMID: 36251998 Free PMC article.
Novel pathomechanisms in inflammatory neuropathies.
Schafflick D, Kieseier BC, Wiendl H, Meyer Zu Horste G. Schafflick D, et al. J Neuroinflammation. 2017 Nov 28;14(1):232. doi: 10.1186/s12974-017-1001-8. J Neuroinflammation. 2017. PMID: 29179723 Free PMC article. Review.
Dysregulation of a specific immune-related network of genes biologically defines a subset of schizophrenia.
Trossbach SV, Hecher L, Schafflick D, Deenen R, Popa O, Lautwein T, Tschirner S, Köhrer K, Fehsel K, Papazova I, Malchow B, Hasan A, Winterer G, Schmitt A, Meyer Zu Hörste G, Falkai P, Korth C. Trossbach SV, et al. Among authors: schafflick d. Transl Psychiatry. 2019 May 31;9(1):156. doi: 10.1038/s41398-019-0486-6. Transl Psychiatry. 2019. PMID: 31150013 Free PMC article.
Enhanced pathogenicity of Th17 cells due to natalizumab treatment: Implications for MS disease rebound.
Janoschka C, Lindner M, Koppers N, Starost L, Liebmann M, Eschborn M, Schneider-Hohendorf T, Windener F, Schafflick D, Fleck AK, Koch K, Deffner M, Schwarze AS, Schulte-Mecklenbeck A, Metz I, Meuth SG, Gross CC, Meyer Zu Hörste G, Schwab N, Kuhlmann T, Wiendl H, Stoll M, Klotz L. Janoschka C, et al. Among authors: schafflick d. Proc Natl Acad Sci U S A. 2023 Jan 3;120(1):e2209944120. doi: 10.1073/pnas.2209944120. Epub 2022 Dec 27. Proc Natl Acad Sci U S A. 2023. PMID: 36574650 Free PMC article.