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Glioblastoma-infiltrating CD8+ T cells are predominantly a clonally expanded GZMK+ effector population.
Wang AZ, Mashimo BL, Schaettler MO, Sherpa ND, Leavitt LA, Livingstone AJ, Khan SM, Li M, Anzaldua-Campos MI, Bradley JD, Leuthardt EC, Kim AH, Dowling JL, Chicoine MR, Jones PS, Choi BD, Cahill DP, Carter BS, Petti AA, Johanns TM, Dunn GP. Wang AZ, et al. Among authors: schaettler mo. Cancer Discov. 2024 Feb 28. doi: 10.1158/2159-8290.CD-23-0913. Online ahead of print. Cancer Discov. 2024. PMID: 38416133
The Conventional Dendritic Cell 1 Subset Primes CD8+ T Cells and Traffics Tumor Antigen to Drive Antitumor Immunity in the Brain.
Bowman-Kirigin JA, Desai R, Saunders BT, Wang AZ, Schaettler MO, Liu CJ, Livingstone AJ, Kobayashi DK, Durai V, Kretzer NM, Zipfel GJ, Leuthardt EC, Osbun JW, Chicoine MR, Kim AH, Murphy KM, Johanns TM, Zinselmeyer BH, Dunn GP. Bowman-Kirigin JA, et al. Among authors: schaettler mo. Cancer Immunol Res. 2023 Jan 3;11(1):20-37. doi: 10.1158/2326-6066.CIR-22-0098. Cancer Immunol Res. 2023. PMID: 36409838 Free PMC article.
Characterization of the Genomic and Immunologic Diversity of Malignant Brain Tumors through Multisector Analysis.
Schaettler MO, Richters MM, Wang AZ, Skidmore ZL, Fisk B, Miller KE, Vickery TL, Kim AH, Chicoine MR, Osbun JW, Leuthardt EC, Dowling JL, Zipfel GJ, Dacey RG, Lu HC, Johanns TM, Griffith OL, Mardis ER, Griffith M, Dunn GP. Schaettler MO, et al. Cancer Discov. 2022 Jan;12(1):154-171. doi: 10.1158/2159-8290.CD-21-0291. Epub 2021 Oct 5. Cancer Discov. 2022. PMID: 34610950 Free PMC article.
GATA2 Regulates Constitutive PD-L1 and PD-L2 Expression in Brain Tumors.
Fu Y, Liu CJ, Kobayashi DK, Johanns TM, Bowman-Kirigin JA, Schaettler MO, Mao DD, Bender D, Kelley DG, Uppaluri R, Bi WL, Dunn IF, Tao Y, Luo J, Kim AH, Dunn GP. Fu Y, et al. Among authors: schaettler mo. Sci Rep. 2020 Jun 3;10(1):9027. doi: 10.1038/s41598-020-65915-z. Sci Rep. 2020. PMID: 32493985 Free PMC article.