Schaeffer P - Search Results

1

Inhibition of tumor angiogenesis and growth by a small-molecule multi-FGF receptor blocker with allosteric properties.

Bono F, De Smet F, Herbert C, De Bock K, Georgiadou M, Fons P, Tjwa M, Alcouffe C, Ny A, Bianciotto M, Jonckx B, Murakami M, Lanahan AA, Michielsen C, Sibrac D, Dol-Gleizes F, Mazzone M, Zacchigna S, Herault JP, Fischer C, Rigon P, Ruiz de Almodovar C, Claes F, Blanc I, Poesen K, Zhang J, Segura I, Gueguen G, Bordes MF, Lambrechts D, Broussy R, van de Wouwer M, Michaux C, Shimada T, Jean I, Blacher S, Noel A, Motte P, Rom E, Rakic JM, Katsuma S, Schaeffer P, Yayon A, Van Schepdael A, Schwalbe H, Gervasio FL, Carmeliet G, Rozensky J, Dewerchin M, Simons M, Christopoulos A, Herbert JM, Carmeliet P. Bono F, et al. Among authors: schaeffer p. Cancer Cell. 2013 Apr 15;23(4):477-88. doi: 10.1016/j.ccr.2013.02.019. Cancer Cell. 2013. PMID: 23597562 Free article.

2

Tumor vasculature is regulated by FGF/FGFR signaling-mediated angiogenesis and bone marrow-derived cell recruitment: this mechanism is inhibited by SSR128129E, the first allosteric antagonist of FGFRs.

Fons P, Gueguen-Dorbes G, Herault JP, Geronimi F, Tuyaret J, Frédérique D, Schaeffer P, Volle-Challier C, Herbert JM, Bono F. Fons P, et al. Among authors: schaeffer p. J Cell Physiol. 2015 Jan;230(1):43-51. doi: 10.1002/jcp.24656. J Cell Physiol. 2015. PMID: 24760775

3

SAR131675, a potent and selective VEGFR-3-TK inhibitor with antilymphangiogenic, antitumoral, and antimetastatic activities.

Alam A, Blanc I, Gueguen-Dorbes G, Duclos O, Bonnin J, Barron P, Laplace MC, Morin G, Gaujarengues F, Dol F, Hérault JP, Schaeffer P, Savi P, Bono F. Alam A, et al. Among authors: schaeffer p. Mol Cancer Ther. 2012 Aug;11(8):1637-49. doi: 10.1158/1535-7163.MCT-11-0866-T. Epub 2012 May 14. Mol Cancer Ther. 2012. PMID: 22584122

4

A new synthetic FGF receptor antagonist inhibits arteriosclerosis in a mouse vein graft model and atherosclerosis in apolipoprotein E-deficient mice.

Dol-Gleizes F, Delesque-Touchard N, Marès AM, Nestor AL, Schaeffer P, Bono F. Dol-Gleizes F, et al. Among authors: schaeffer p. PLoS One. 2013 Nov 4;8(11):e80027. doi: 10.1371/journal.pone.0080027. eCollection 2013. PLoS One. 2013. PMID: 24224032 Free PMC article.

5

Preclinical evidence that SSR128129E--a novel small-molecule multi-fibroblast growth factor receptor blocker--radiosensitises human glioblastoma.

Ader I, Delmas C, Skuli N, Bonnet J, Schaeffer P, Bono F, Cohen-Jonathan-Moyal E, Toulas C. Ader I, et al. Among authors: schaeffer p. Eur J Cancer. 2014 Sep;50(13):2351-9. doi: 10.1016/j.ejca.2014.05.012. Epub 2014 Jun 18. Eur J Cancer. 2014. PMID: 24953334

6

Factor Xa activates endothelial cells by a receptor cascade between EPR-1 and PAR-2.

Bono F, Schaeffer P, Hérault JP, Michaux C, Nestor AL, Guillemot JC, Herbert JM. Bono F, et al. Among authors: schaeffer p. Arterioscler Thromb Vasc Biol. 2000 Nov;20(11):E107-12. doi: 10.1161/01.atv.20.11.e107. Arterioscler Thromb Vasc Biol. 2000. PMID: 11073863

7

Human umbilical vein endothelial cells express high affinity receptors for factor Xa.

Bono F, Herault JP, Avril C, Schaeffer P, Lormeau JC, Herbert JM. Bono F, et al. Among authors: schaeffer p. J Cell Physiol. 1997 Jul;172(1):36-43. doi: 10.1002/(SICI)1097-4652(199707)172:1<36::AID-JCP4>3.0.CO;2-E. J Cell Physiol. 1997. PMID: 9207923

8

Activation of human vascular endothelial cells by factor Xa: effect of specific inhibitors.

Herault JP, Bono F, Avril C, Schaeffer P, Herbert JM. Herault JP, et al. Among authors: schaeffer p. Biochem Pharmacol. 1999 Mar 15;57(6):603-10. doi: 10.1016/s0006-2952(98)00348-7. Biochem Pharmacol. 1999. PMID: 10037444

9

Nonproteolytic activation of the thrombin receptor promotes human umbilical vein endothelial cell growth but not intracellular CA2+, prostacyclin, or permeability.

Schaeffer P, Riera E, Dupuy E, Herbert JM. Schaeffer P, et al. Biochem Pharmacol. 1997 Feb 21;53(4):487-91. doi: 10.1016/s0006-2952(96)00735-6. Biochem Pharmacol. 1997. PMID: 9105399

10

Pharmacokinetics of new synthetic heparin mimetics.

Hérault JP, Bernat A, Roye F, Michaux C, Schaeffer P, Bono F, Petitou M, Herbert JM. Hérault JP, et al. Among authors: schaeffer p. Thromb Haemost. 2002 Jun;87(6):985-9. Thromb Haemost. 2002. PMID: 12083506

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

277 results

Search Page