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Covalent Proximity Scanning of a Distal Cysteine to Target PI3Kα.
Borsari C, Keles E, McPhail JA, Schaefer A, Sriramaratnam R, Goch W, Schaefer T, De Pascale M, Bal W, Gstaiger M, Burke JE, Wymann MP. Borsari C, et al. Among authors: schaefer a, schaefer t. J Am Chem Soc. 2022 Apr 13;144(14):6326-6342. doi: 10.1021/jacs.1c13568. Epub 2022 Mar 30. J Am Chem Soc. 2022. PMID: 35353516 Free PMC article.
Investigation of morpholine isosters for the development of a potent, selective and metabolically stable mTOR kinase inhibitor.
De Pascale M, Bissegger L, Tarantelli C, Beaufils F, Prescimone A, Mohamed Seid Hedad H, Kayali O, Orbegozo C, Raguž L, Schaefer T, Hebeisen P, Bertoni F, Wymann MP, Borsari C. De Pascale M, et al. Among authors: schaefer t. Eur J Med Chem. 2023 Feb 15;248:115038. doi: 10.1016/j.ejmech.2022.115038. Epub 2022 Dec 28. Eur J Med Chem. 2023. PMID: 36634458 Free article.
AKT-driven phospho-patterns of pluripotency.
Schaefer T, Lengerke C. Schaefer T, et al. Cell Cycle. 2015;14(24):3784-5. doi: 10.1080/15384101.2015.1115642. Cell Cycle. 2015. PMID: 26697835 Free PMC article. No abstract available.
Molecular and functional interactions between AKT and SOX2 in breast carcinoma.
Schaefer T, Wang H, Mir P, Konantz M, Pereboom TC, Paczulla AM, Merz B, Fehm T, Perner S, Rothfuss OC, Kanz L, Schulze-Osthoff K, Lengerke C. Schaefer T, et al. Oncotarget. 2015 Dec 22;6(41):43540-56. doi: 10.18632/oncotarget.6183. Oncotarget. 2015. PMID: 26498353 Free PMC article.
Ecotropic viral integration site 1, a novel oncogene in prostate cancer.
Queisser A, Hagedorn S, Wang H, Schaefer T, Konantz M, Alavi S, Deng M, Vogel W, von Mässenhausen A, Kristiansen G, Duensing S, Kirfel J, Lengerke C, Perner S. Queisser A, et al. Among authors: schaefer t. Oncogene. 2017 Mar;36(11):1573-1584. doi: 10.1038/onc.2016.325. Epub 2016 Sep 12. Oncogene. 2017. PMID: 27617580
Prominent Oncogenic Roles of EVI1 in Breast Carcinoma.
Wang H, Schaefer T, Konantz M, Braun M, Varga Z, Paczulla AM, Reich S, Jacob F, Perner S, Moch H, Fehm TN, Kanz L, Schulze-Osthoff K, Lengerke C. Wang H, et al. Among authors: schaefer t. Cancer Res. 2017 Apr 15;77(8):2148-2160. doi: 10.1158/0008-5472.CAN-16-0593. Epub 2017 Feb 16. Cancer Res. 2017. PMID: 28209621 Free article.
Regulation of glioma cell invasion by 3q26 gene products PIK3CA, SOX2 and OPA1.
Schaefer T, Ramadoss A, Leu S, Tintignac L, Tostado C, Bink A, Schürch C, Müller J, Schärer J, Moffa G, Demougin P, Moes S, Stippich C, Falbo S, Neddersen H, Bucher H, Frank S, Jenö P, Lengerke C, Ritz MF, Mariani L, Boulay JL. Schaefer T, et al. Brain Pathol. 2019 May;29(3):336-350. doi: 10.1111/bpa.12670. Epub 2018 Dec 21. Brain Pathol. 2019. PMID: 30403311 Free PMC article.
318 results