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Combination of common mtDNA variants results in mitochondrial dysfunction and a connective tissue dysregulation.
Schaefer PM, Scherer Alves L, Lvova M, Huang J, Rathi K, Janssen K, Butic A, Yardeni T, Morrow R, Lott M, Murdock D, Song A, Keller K, Garcia BA, Francomano CA, Wallace DC. Schaefer PM, et al. Proc Natl Acad Sci U S A. 2022 Nov 8;119(45):e2212417119. doi: 10.1073/pnas.2212417119. Epub 2022 Nov 2. Proc Natl Acad Sci U S A. 2022. PMID: 36322731 Free PMC article.
Regulation of nuclear epigenome by mitochondrial DNA heteroplasmy.
Kopinski PK, Janssen KA, Schaefer PM, Trefely S, Perry CE, Potluri P, Tintos-Hernandez JA, Singh LN, Karch KR, Campbell SL, Doan MT, Jiang H, Nissim I, Nakamaru-Ogiso E, Wellen KE, Snyder NW, Garcia BA, Wallace DC. Kopinski PK, et al. Among authors: schaefer pm. Proc Natl Acad Sci U S A. 2019 Aug 6;116(32):16028-16035. doi: 10.1073/pnas.1906896116. Epub 2019 Jun 28. Proc Natl Acad Sci U S A. 2019. PMID: 31253706 Free PMC article.
Host mitochondria influence gut microbiome diversity: A role for ROS.
Yardeni T, Tanes CE, Bittinger K, Mattei LM, Schaefer PM, Singh LN, Wu GD, Murdock DG, Wallace DC. Yardeni T, et al. Among authors: schaefer pm. Sci Signal. 2019 Jul 2;12(588):eaaw3159. doi: 10.1126/scisignal.aaw3159. Sci Signal. 2019. PMID: 31266851
NADH Fluorescence Lifetime Imaging Microscopy Reveals Selective Mitochondrial Dysfunction in Neurons Overexpressing Alzheimer's Disease-Related Proteins.
Niederschweiberer MA, Schaefer PM, Singh LN, Lausser L, Bhosale D, Hesse R, Calzia E, Kestler HA, Rueck A, Wallace DC, von Einem B, von Arnim CAF. Niederschweiberer MA, et al. Among authors: schaefer pm. Front Mol Biosci. 2021 Jun 14;8:671274. doi: 10.3389/fmolb.2021.671274. eCollection 2021. Front Mol Biosci. 2021. PMID: 34195227 Free PMC article.
Single-cell NAD(H) levels predict clonal lymphocyte expansion dynamics.
Turner L, Van Le TN, Cross E, Queriault C, Knight M, Trihemasava K, Davis J, Schaefer P, Nguyen J, Xu J, Goldspiel B, Hall E, Rome K, Scaglione M, Eggert J, Au-Yeung B, Wallace DC, Mesaros C, Baur JA, Bailis W. Turner L, et al. Sci Immunol. 2024 Mar 15;9(93):eadj7238. doi: 10.1126/sciimmunol.adj7238. Epub 2024 Mar 15. Sci Immunol. 2024. PMID: 38489349 Free PMC article.
28 results