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SpotOn: High Accuracy Identification of Protein-Protein Interface Hot-Spots.
Moreira IS, Koukos PI, Melo R, Almeida JG, Preto AJ, Schaarschmidt J, Trellet M, Gümüş ZH, Costa J, Bonvin AMJJ. Moreira IS, et al. Among authors: schaarschmidt j. Sci Rep. 2017 Aug 14;7(1):8007. doi: 10.1038/s41598-017-08321-2. Sci Rep. 2017. PMID: 28808256 Free PMC article.
Natural helix 9 mutants of PPARγ differently affect its transcriptional activity.
Broekema MF, Massink MPG, Donato C, de Ligt J, Schaarschmidt J, Borgman A, Schooneman MG, Melchers D, Gerding MN, Houtman R, Bonvin AMJJ, Majithia AR, Monajemi H, van Haaften GW, Soeters MR, Kalkhoven E. Broekema MF, et al. Among authors: schaarschmidt j. Mol Metab. 2019 Feb;20:115-127. doi: 10.1016/j.molmet.2018.12.005. Epub 2018 Dec 16. Mol Metab. 2019. PMID: 30595551 Free PMC article.
West-Life: A Virtual Research Environment for structural biology.
Morris C, Andreetto P, Banci L, Bonvin AMJJ, Chojnowski G, Cano LD, Carazo JM, Conesa P, Daenke S, Damaskos G, Giachetti A, Haley NEC, Hekkelman ML, Heuser P, Joosten RP, Kouřil D, Křenek A, Kulhánek T, Lamzin VS, Nadzirin N, Perrakis A, Rosato A, Sanderson F, Segura J, Schaarschmidt J, Sobolev E, Traldi S, Trellet ME, Velankar S, Verlato M, Winn M. Morris C, et al. Among authors: schaarschmidt j. J Struct Biol X. 2019 Feb 26;1:100006. doi: 10.1016/j.yjsbx.2019.100006. eCollection 2019 Jan-Mar. J Struct Biol X. 2019. PMID: 32647812 Free PMC article.
A newly discovered TSHR variant (L665F) associated with nonautoimmune hyperthyroidism in an Austrian family induces constitutive TSHR activation by steric repulsion between TM1 and TM7.
Jaeschke H, Schaarschmidt J, Eszlinger M, Huth S, Puttinger R, Rittinger O, Meiler J, Paschke R. Jaeschke H, et al. Among authors: schaarschmidt j. J Clin Endocrinol Metab. 2014 Oct;99(10):E2051-9. doi: 10.1210/jc.2014-1436. Epub 2014 Jun 20. J Clin Endocrinol Metab. 2014. PMID: 24947036
295 results