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Protein production and purification.
Structural Genomics Consortium; China Structural Genomics Consortium; Northeast Structural Genomics Consortium; Gräslund S, Nordlund P, Weigelt J, Hallberg BM, Bray J, Gileadi O, Knapp S, Oppermann U, Arrowsmith C, Hui R, Ming J, dhe-Paganon S, Park HW, Savchenko A, Yee A, Edwards A, Vincentelli R, Cambillau C, Kim R, Kim SH, Rao Z, Shi Y, Terwilliger TC, Kim CY, Hung LW, Waldo GS, Peleg Y, Albeck S, Unger T, Dym O, Prilusky J, Sussman JL, Stevens RC, Lesley SA, Wilson IA, Joachimiak A, Collart F, Dementieva I, Donnelly MI, Eschenfeldt WH, Kim Y, Stols L, Wu R, Zhou M, Burley SK, Emtage JS, Sauder JM, Thompson D, Bain K, Luz J, Gheyi T, Zhang F, Atwell S, Almo SC, Bonanno JB, Fiser A, Swaminathan S, Studier FW, Chance MR, Sali A, Acton TB, Xiao R, Zhao L, Ma LC, Hunt JF, Tong L, Cunningham K, Inouye M, Anderson S, Janjua H, Shastry R, Ho CK, Wang D, Wang H, Jiang M, Montelione GT, Stuart DI, Owens RJ, Daenke S, Schütz A, Heinemann U, Yokoyama S, Büssow K, Gunsalus KC. Structural Genomics Consortium, et al. Among authors: schutz a. Nat Methods. 2008 Feb;5(2):135-46. doi: 10.1038/nmeth.f.202. Nat Methods. 2008. PMID: 18235434 Free PMC article. Review.
The Lin28 cold-shock domain remodels pre-let-7 microRNA.
Mayr F, Schütz A, Döge N, Heinemann U. Mayr F, et al. Among authors: schutz a. Nucleic Acids Res. 2012 Aug;40(15):7492-506. doi: 10.1093/nar/gks355. Epub 2012 May 8. Nucleic Acids Res. 2012. PMID: 22570413 Free PMC article.
Usa1 functions as a scaffold of the HRD-ubiquitin ligase.
Horn SC, Hanna J, Hirsch C, Volkwein C, Schütz A, Heinemann U, Sommer T, Jarosch E. Horn SC, et al. Among authors: schutz a. Mol Cell. 2009 Dec 11;36(5):782-93. doi: 10.1016/j.molcel.2009.10.015. Mol Cell. 2009. PMID: 20005842 Free article.
Tricellulin is a target of the ubiquitin ligase Itch.
Jennek S, Mittag S, Reiche J, Westphal JK, Seelk S, Dörfel MJ, Pfirrmann T, Friedrich K, Schütz A, Heinemann U, Huber O. Jennek S, et al. Among authors: schutz a. Ann N Y Acad Sci. 2017 Jun;1397(1):157-168. doi: 10.1111/nyas.13349. Epub 2017 Apr 24. Ann N Y Acad Sci. 2017. PMID: 28436082
Structure-Based Design of Xanthine-Benzimidazole Derivatives as Novel and Potent Tryptophan Hydroxylase Inhibitors.
Specker E, Matthes S, Wesolowski R, Schütz A, Grohmann M, Alenina N, Pleimes D, Mallow K, Neuenschwander M, Gogolin A, Weise M, Pfeifer J, Ziebart N, Heinemann U, von Kries JP, Nazaré M, Bader M. Specker E, et al. Among authors: schutz a. J Med Chem. 2022 Aug 25;65(16):11126-11149. doi: 10.1021/acs.jmedchem.2c00598. Epub 2022 Aug 3. J Med Chem. 2022. PMID: 35921615
Phenylalanine hydroxylase contributes to serotonin synthesis in mice.
Mordhorst A, Dhandapani P, Matthes S, Mosienko V, Rothe M, Todiras M, Self J, Schunck WH, Schütz A, Bader M, Alenina N. Mordhorst A, et al. Among authors: schutz a. FASEB J. 2021 Jun;35(6):e21648. doi: 10.1096/fj.202100366R. FASEB J. 2021. PMID: 33993565
613 results