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PI3Kβ inhibition enhances ALK-inhibitor sensitivity in ALK-rearranged lung cancer.
Talwelkar SS, Mäyränpää MI, Schüler J, Linnavirta N, Hemmes A, Adinolfi S, Kankainen M, Sommergruber W, Levonen AL, Räsänen J, Knuuttila A, Verschuren EW, Wennerberg K. Talwelkar SS, et al. Among authors: schuler j. Mol Oncol. 2023 May;17(5):747-764. doi: 10.1002/1878-0261.13342. Epub 2023 Jan 25. Mol Oncol. 2023. PMID: 36423211 Free PMC article.
Stromal-derived IGF2 promotes colon cancer progression via paracrine and autocrine mechanisms.
Unger C, Kramer N, Unterleuthner D, Scherzer M, Burian A, Rudisch A, Stadler M, Schlederer M, Lenhardt D, Riedl A, Walter S, Wernitznig A, Kenner L, Hengstschläger M, Schüler J, Sommergruber W, Dolznig H. Unger C, et al. Among authors: schuler j. Oncogene. 2017 Sep 21;36(38):5341-5355. doi: 10.1038/onc.2017.116. Epub 2017 May 22. Oncogene. 2017. PMID: 28534511
Stromal fibroblasts shape the myeloid phenotype in normal colon and colorectal cancer and induce CD163 and CCL2 expression in macrophages.
Stadler M, Pudelko K, Biermeier A, Walterskirchen N, Gaigneaux A, Weindorfer C, Harrer N, Klett H, Hengstschläger M, Schüler J, Sommergruber W, Oehler R, Bergmann M, Letellier E, Dolznig H. Stadler M, et al. Among authors: schuler j. Cancer Lett. 2021 Nov 1;520:184-200. doi: 10.1016/j.canlet.2021.07.006. Epub 2021 Jul 10. Cancer Lett. 2021. PMID: 34256095 Free article.
Autocrine WNT2 signaling in fibroblasts promotes colorectal cancer progression.
Kramer N, Schmöllerl J, Unger C, Nivarthi H, Rudisch A, Unterleuthner D, Scherzer M, Riedl A, Artaker M, Crncec I, Lenhardt D, Schwarz T, Prieler B, Han X, Hengstschläger M, Schüler J, Eferl R, Moriggl R, Sommergruber W, Dolznig H. Kramer N, et al. Among authors: schuler j. Oncogene. 2017 Sep 28;36(39):5460-5472. doi: 10.1038/onc.2017.144. Epub 2017 May 29. Oncogene. 2017. PMID: 28553956
The isothiocyanate erucin abrogates telomerase in hepatocellular carcinoma cells in vitro and in an orthotopic xenograft tumour model of HCC.
Herz C, Hertrampf A, Zimmermann S, Stetter N, Wagner M, Kleinhans C, Erlacher M, Schüler J, Platz S, Rohn S, Mersch-Sundermann V, Lamy E. Herz C, et al. Among authors: schuler j. J Cell Mol Med. 2014 Dec;18(12):2393-403. doi: 10.1111/jcmm.12412. Epub 2014 Sep 25. J Cell Mol Med. 2014. PMID: 25256442 Free PMC article.
ZEB1-associated drug resistance in cancer cells is reversed by the class I HDAC inhibitor mocetinostat.
Meidhof S, Brabletz S, Lehmann W, Preca BT, Mock K, Ruh M, Schüler J, Berthold M, Weber A, Burk U, Lübbert M, Puhr M, Culig Z, Wellner U, Keck T, Bronsert P, Küsters S, Hopt UT, Stemmler MP, Brabletz T. Meidhof S, et al. Among authors: schuler j. EMBO Mol Med. 2015 Jun;7(6):831-47. doi: 10.15252/emmm.201404396. EMBO Mol Med. 2015. PMID: 25872941 Free PMC article.
Phenotypic drug screening and target validation for improved personalized therapy reveal the complexity of phenotype-genotype correlations in clear cell renal cell carcinoma.
Schneider M, Schüler J, Höfflin R, Korzeniewski N, Grüllich C, Roth W, Teber D, Hadaschik B, Pahernik S, Hohenfellner M, Duensing S. Schneider M, et al. Among authors: schuler j. Urol Oncol. 2014 Aug;32(6):877-84. doi: 10.1016/j.urolonc.2014.03.011. Epub 2014 Jun 11. Urol Oncol. 2014. PMID: 24929890
311 results