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Structure-guided design of a selective inhibitor of the methyltransferase KMT9 with cellular activity.
Nat Commun. 2024 Jan 2;15(1):43. doi: 10.1038/s41467-023-44243-6.
Nat Commun. 2024.
PMID: 38167811
Free PMC article.
Assembly of methylated KDM1A and CHD1 drives androgen receptor-dependent transcription and translocation.
Metzger E, Willmann D, McMillan J, Forne I, Metzger P, Gerhardt S, Petroll K, von Maessenhausen A, Urban S, Schott AK, Espejo A, Eberlin A, Wohlwend D, Schüle KM, Schleicher M, Perner S, Bedford MT, Jung M, Dengjel J, Flaig R, Imhof A, Einsle O, Schüle R.
Metzger E, et al. Among authors: schule km.
Nat Struct Mol Biol. 2016 Feb;23(2):132-9. doi: 10.1038/nsmb.3153. Epub 2016 Jan 11.
Nat Struct Mol Biol. 2016.
PMID: 26751641
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Eomes restricts Brachyury functions at the onset of mouse gastrulation.
Schüle KM, Weckerle J, Probst S, Wehmeyer AE, Zissel L, Schröder CM, Tekman M, Kim GJ, Schlägl IM, Sagar, Arnold SJ.
Schüle KM, et al.
Dev Cell. 2023 Sep 25;58(18):1627-1642.e7. doi: 10.1016/j.devcel.2023.07.023. Epub 2023 Aug 25.
Dev Cell. 2023.
PMID: 37633271
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Chimeric 3D gastruloids - a versatile tool for studies of mammalian peri-gastrulation development.
Wehmeyer AE, Schüle KM, Conrad A, Schröder CM, Probst S, Arnold SJ.
Wehmeyer AE, et al. Among authors: schule km.
Development. 2022 Nov 15;149(22):dev200812. doi: 10.1242/dev.200812. Epub 2022 Nov 21.
Development. 2022.
PMID: 36326003
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NEIL1 and NEIL2 DNA glycosylases protect neural crest development against mitochondrial oxidative stress.
Han D, Schomacher L, Schüle KM, Mallick M, Musheev MU, Karaulanov E, Krebs L, von Seggern A, Niehrs C.
Han D, et al. Among authors: schule km.
Elife. 2019 Sep 30;8:e49044. doi: 10.7554/eLife.49044.
Elife. 2019.
PMID: 31566562
Free PMC article.
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GADD45 promotes locus-specific DNA demethylation and 2C cycling in embryonic stem cells.
Schüle KM, Leichsenring M, Andreani T, Vastolo V, Mallick M, Musheev MU, Karaulanov E, Niehrs C.
Schüle KM, et al.
Genes Dev. 2019 Jul 1;33(13-14):782-798. doi: 10.1101/gad.325696.119. Epub 2019 Jun 6.
Genes Dev. 2019.
PMID: 31171699
Free PMC article.
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