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Combinatorial effects on gene expression at the Lbx1/Fgf8 locus resolve split-hand/foot malformation type 3.
Cova G, Glaser J, Schöpflin R, Prada-Medina CA, Ali S, Franke M, Falcone R, Federer M, Ponzi E, Ficarella R, Novara F, Wittler L, Timmermann B, Gentile M, Zuffardi O, Spielmann M, Mundlos S. Cova G, et al. Among authors: schopflin r. Nat Commun. 2023 Mar 17;14(1):1475. doi: 10.1038/s41467-023-37057-z. Nat Commun. 2023. PMID: 36928426 Free PMC article.
Changing chromatin fiber conformation by nucleosome repositioning.
Müller O, Kepper N, Schöpflin R, Ettig R, Rippe K, Wedemann G. Müller O, et al. Among authors: schopflin r. Biophys J. 2014 Nov 4;107(9):2141-50. doi: 10.1016/j.bpj.2014.09.026. Biophys J. 2014. PMID: 25418099 Free PMC article.
Single-drop optimization of protein crystallization.
Meyer A, Dierks K, Hilterhaus D, Klupsch T, Mühlig P, Kleesiek J, Schöpflin R, Einspahr H, Hilgenfeld R, Betzel C. Meyer A, et al. Among authors: schopflin r. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Aug 1;68(Pt 8):994-8. doi: 10.1107/S1744309112024074. Epub 2012 Jul 31. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012. PMID: 22869140 Free PMC article.
Formation of new chromatin domains determines pathogenicity of genomic duplications.
Franke M, Ibrahim DM, Andrey G, Schwarzer W, Heinrich V, Schöpflin R, Kraft K, Kempfer R, Jerković I, Chan WL, Spielmann M, Timmermann B, Wittler L, Kurth I, Cambiaso P, Zuffardi O, Houge G, Lambie L, Brancati F, Pombo A, Vingron M, Spitz F, Mundlos S. Franke M, et al. Among authors: schopflin r. Nature. 2016 Oct 13;538(7624):265-269. doi: 10.1038/nature19800. Epub 2016 Oct 5. Nature. 2016. PMID: 27706140
33 results