Schäfer MKE - Search Results

1

Analysis of hyperforin (St. John's wort) action at TRPC6 channel leads to the development of a new class of antidepressant drugs.

El Hamdaoui Y, Zheng F, Fritz N, Ye L, Tran MA, Schwickert K, Schirmeister T, Braeuning A, Lichtenstein D, Hellmich UA, Weikert D, Heinrich M, Treccani G, Schäfer MKE, Nowak G, Nürnberg B, Alzheimer C, Müller CP, Friedland K. El Hamdaoui Y, et al. Among authors: schafer mke. Mol Psychiatry. 2022 Dec;27(12):5070-5085. doi: 10.1038/s41380-022-01804-3. Epub 2022 Oct 12. Mol Psychiatry. 2022. PMID: 36224261 Free PMC article.

2

Neuronal Growth and Behavioral Alterations in Mice Deficient for the Psychiatric Disease-Associated Negr1 Gene.

Singh K, Loreth D, Pöttker B, Hefti K, Innos J, Schwald K, Hengstler H, Menzel L, Sommer CJ, Radyushkin K, Kretz O, Philips MA, Haas CA, Frauenknecht K, Lilleväli K, Heimrich B, Vasar E, Schäfer MKE. Singh K, et al. Among authors: schafer mke. Front Mol Neurosci. 2018 Feb 9;11:30. doi: 10.3389/fnmol.2018.00030. eCollection 2018. Front Mol Neurosci. 2018. PMID: 29479305 Free PMC article.

3

Extracellular signal-regulated kinase-dependent phosphorylation of histone H3 serine 10 is involved in the pathogenesis of traumatic brain injury.

Zhang Y, Yang X, Hou X, Zhou W, Bi C, Yang Z, Lu S, Ding Z, Ding Z, Zou Y, Guo Q, Schäfer MKE, Huang C. Zhang Y, et al. Among authors: schafer mke. Front Mol Neurosci. 2022 Sep 29;15:828567. doi: 10.3389/fnmol.2022.828567. eCollection 2022. Front Mol Neurosci. 2022. PMID: 36245918 Free PMC article.

4

Loss of synaptic zinc transport in progranulin deficient mice may contribute to progranulin-associated psychopathology and chronic pain.

Hardt S, Heidler J, Albuquerque B, Valek L, Altmann C, Wilken-Schmitz A, Schäfer MKE, Wittig I, Tegeder I. Hardt S, et al. Among authors: schafer mke. Biochim Biophys Acta Mol Basis Dis. 2017 Nov;1863(11):2727-2745. doi: 10.1016/j.bbadis.2017.07.014. Epub 2017 Jul 15. Biochim Biophys Acta Mol Basis Dis. 2017. PMID: 28720486 Free article.

5

Early posttraumatic CSF1R inhibition via PLX3397 leads to time- and sex-dependent effects on inflammation and neuronal maintenance after traumatic brain injury in mice.

Wang Y, Wernersbach I, Strehle J, Li S, Appel D, Klein M, Ritter K, Hummel R, Tegeder I, Schäfer MKE. Wang Y, et al. Among authors: schafer mke. Brain Behav Immun. 2022 Nov;106:49-66. doi: 10.1016/j.bbi.2022.07.164. Epub 2022 Aug 3. Brain Behav Immun. 2022. PMID: 35933030 Free article.

6

Repurposing of pexidartinib for microglia depletion and renewal.

Weyer MP, Strehle J, Schäfer MKE, Tegeder I. Weyer MP, et al. Among authors: schafer mke. Pharmacol Ther. 2024 Jan;253:108565. doi: 10.1016/j.pharmthera.2023.108565. Epub 2023 Dec 3. Pharmacol Ther. 2024. PMID: 38052308 Review.

7

Proneurotrophin Binding to P75 Neurotrophin Receptor (P75ntr) Is Essential for Brain Lesion Formation and Functional Impairment after Experimental Traumatic Brain Injury.

Sebastiani A, Gölz C, Werner C, Schäfer MK, Engelhard K, Thal SC. Sebastiani A, et al. J Neurotrauma. 2015 Oct 15;32(20):1599-607. doi: 10.1089/neu.2014.3751. Epub 2015 Jun 30. J Neurotrauma. 2015. PMID: 25879397

8

Low brain endocannabinoids associated with persistent non-goal directed nighttime hyperactivity after traumatic brain injury in mice.

Vogel A, Wilken-Schmitz A, Hummel R, Lang M, Gurke R, Schreiber Y, Schäfer MKE, Tegeder I. Vogel A, et al. Among authors: schafer mke. Sci Rep. 2020 Sep 10;10(1):14929. doi: 10.1038/s41598-020-71879-x. Sci Rep. 2020. PMID: 32913220 Free PMC article.

9

2-Methoxyestradiol confers neuroprotection and inhibits a maladaptive HIF-1α response after traumatic brain injury in mice.

Schaible EV, Windschügl J, Bobkiewicz W, Kaburov Y, Dangel L, Krämer T, Huang C, Sebastiani A, Luh C, Werner C, Engelhard K, Thal SC, Schäfer MK. Schaible EV, et al. J Neurochem. 2014 Jun;129(6):940-54. doi: 10.1111/jnc.12708. Epub 2014 Apr 2. J Neurochem. 2014. PMID: 24606183 Free article.

10

Pharmacologic Inhibition of ADAM10 Attenuates Brain Tissue Loss, Axonal Injury and Pro-inflammatory Gene Expression Following Traumatic Brain Injury in Mice.

Appel D, Hummel R, Weidemeier M, Endres K, Gölz C, Schäfer MKE. Appel D, et al. Among authors: schafer mke. Front Cell Dev Biol. 2021 Mar 15;9:661462. doi: 10.3389/fcell.2021.661462. eCollection 2021. Front Cell Dev Biol. 2021. PMID: 33791311 Free PMC article.

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