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Non-canonical functions of UHRF1 maintain DNA methylation homeostasis in cancer cells.
Yamaguchi K, Chen X, Rodgers B, Miura F, Bashtrykov P, Bonhomme F, Salinas-Luypaert C, Haxholli D, Gutekunst N, Aygenli BÖ, Ferry L, Kirsh O, Laisné M, Scelfo A, Ugur E, Arimondo PB, Leonhardt H, Kanemaki MT, Bartke T, Fachinetti D, Jeltsch A, Ito T, Defossez PA. Yamaguchi K, et al. Among authors: scelfo a. Nat Commun. 2024 Apr 5;15(1):2960. doi: 10.1038/s41467-024-47314-4. Nat Commun. 2024. PMID: 38580649 Free PMC article.
Tunable DNMT1 degradation reveals DNMT1/DNMT3B synergy in DNA methylation and genome organization.
Scelfo A, Barra V, Abdennur N, Spracklin G, Busato F, Salinas-Luypaert C, Bonaiti E, Velasco G, Bonhomme F, Chipont A, Tijhuis AE, Spierings DCJ, Guérin C, Arimondo P, Francastel C, Foijer F, Tost J, Mirny L, Fachinetti D. Scelfo A, et al. J Cell Biol. 2024 Apr 1;223(4):e202307026. doi: 10.1083/jcb.202307026. Epub 2024 Feb 20. J Cell Biol. 2024. PMID: 38376465
Specialized replication mechanisms maintain genome stability at human centromeres.
Scelfo A, Angrisani A, Grillo M, Barnes BM, Muyas F, Sauer CM, Leung CWB, Dumont M, Grison M, Mazaud D, Garnier M, Guintini L, Nelson L, Esashi F, Cortés-Ciriano I, Taylor SS, Déjardin J, Wilhelm T, Fachinetti D. Scelfo A, et al. Mol Cell. 2024 Mar 21;84(6):1003-1020.e10. doi: 10.1016/j.molcel.2024.01.018. Epub 2024 Feb 14. Mol Cell. 2024. PMID: 38359824
Centromere: A Trojan horse for genome stability.
Scelfo A, Fachinetti D. Scelfo A, et al. DNA Repair (Amst). 2023 Oct;130:103569. doi: 10.1016/j.dnarep.2023.103569. Epub 2023 Sep 7. DNA Repair (Amst). 2023. PMID: 37708591 Review.
Phosphorylation of CENP-A on serine 7 does not control centromere function.
Barra V, Logsdon GA, Scelfo A, Hoffmann S, Hervé S, Aslanian A, Nechemia-Arbely Y, Cleveland DW, Black BE, Fachinetti D. Barra V, et al. Among authors: scelfo a. Nat Commun. 2019 Jan 11;10(1):175. doi: 10.1038/s41467-018-08073-1. Nat Commun. 2019. PMID: 30635586 Free PMC article.
The H3K36me2 Methyltransferase Nsd1 Demarcates PRC2-Mediated H3K27me2 and H3K27me3 Domains in Embryonic Stem Cells.
Streubel G, Watson A, Jammula SG, Scelfo A, Fitzpatrick DJ, Oliviero G, McCole R, Conway E, Glancy E, Negri GL, Dillon E, Wynne K, Pasini D, Krogan NJ, Bracken AP, Cagney G. Streubel G, et al. Among authors: scelfo a. Mol Cell. 2018 Apr 19;70(2):371-379.e5. doi: 10.1016/j.molcel.2018.02.027. Epub 2018 Mar 29. Mol Cell. 2018. PMID: 29606589 Free article.
19 results