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Palmitate lipotoxicity in enteric glial cells: Lipid remodeling and mitochondrial ROS are responsible for cyt c release outside mitochondria.
Macchioni L, Petricciuolo M, Davidescu M, Fettucciari K, Scarpelli P, Vitale R, Gatticchi L, Orvietani PL, Marchegiani A, Marconi P, Bassotti G, Corcelli A, Corazzi L. Macchioni L, et al. Among authors: scarpelli p. Biochim Biophys Acta Mol Cell Biol Lipids. 2018 Aug;1863(8):895-908. doi: 10.1016/j.bbalip.2018.04.021. Epub 2018 May 2. Biochim Biophys Acta Mol Cell Biol Lipids. 2018. PMID: 29729479
Clostridium difficile toxin B induces senescence in enteric glial cells: A potential new mechanism of Clostridium difficile pathogenesis.
Fettucciari K, Macchioni L, Davidescu M, Scarpelli P, Palumbo C, Corazzi L, Marchegiani A, Cerquetella M, Spaterna A, Marconi P, Bassotti G. Fettucciari K, et al. Among authors: scarpelli p. Biochim Biophys Acta Mol Cell Res. 2018 Dec;1865(12):1945-1958. doi: 10.1016/j.bbamcr.2018.10.007. Epub 2018 Oct 6. Biochim Biophys Acta Mol Cell Res. 2018. PMID: 30296499 Free article.
Selected cholesterol biosynthesis inhibitors produce accumulation of the intermediate FF-MAS that targets nucleus and activates LXRα in HepG2 cells.
Gatticchi L, Cerra B, Scarpelli P, Macchioni L, Sebastiani B, Gioiello A, Roberti R. Gatticchi L, et al. Among authors: scarpelli p. Biochim Biophys Acta Mol Cell Biol Lipids. 2017 Sep;1862(9):842-852. doi: 10.1016/j.bbalip.2017.05.004. Epub 2017 May 9. Biochim Biophys Acta Mol Cell Biol Lipids. 2017. PMID: 28499814
Ursodeoxycholic acid is a GPBAR1 agonist and resets liver/intestinal FXR signaling in a model of diet-induced dysbiosis and NASH.
Carino A, Biagioli M, Marchianò S, Fiorucci C, Zampella A, Monti MC, Scarpelli P, Ricci P, Distrutti E, Fiorucci S. Carino A, et al. Among authors: scarpelli p. Biochim Biophys Acta Mol Cell Biol Lipids. 2019 Oct;1864(10):1422-1437. doi: 10.1016/j.bbalip.2019.07.006. Epub 2019 Jul 17. Biochim Biophys Acta Mol Cell Biol Lipids. 2019. PMID: 31325638
ROS-independent Nrf2 activation in prostate cancer.
Bellezza I, Scarpelli P, Pizzo SV, Grottelli S, Costanzi E, Minelli A. Bellezza I, et al. Among authors: scarpelli p. Oncotarget. 2017 Jun 28;8(40):67506-67518. doi: 10.18632/oncotarget.18724. eCollection 2017 Sep 15. Oncotarget. 2017. PMID: 28978049 Free PMC article.
GPBAR1 Functions as Gatekeeper for Liver NKT Cells and provides Counterregulatory Signals in Mouse Models of Immune-Mediated Hepatitis.
Biagioli M, Carino A, Fiorucci C, Marchianò S, Di Giorgio C, Roselli R, Magro M, Distrutti E, Bereshchenko O, Scarpelli P, Zampella A, Fiorucci S. Biagioli M, et al. Among authors: scarpelli p. Cell Mol Gastroenterol Hepatol. 2019;8(3):447-473. doi: 10.1016/j.jcmgh.2019.06.003. Epub 2019 Jun 18. Cell Mol Gastroenterol Hepatol. 2019. PMID: 31226434 Free PMC article.
102 results