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NEU3 sialidase is activated under hypoxia and protects skeletal muscle cells from apoptosis through the activation of the epidermal growth factor receptor signaling pathway and the hypoxia-inducible factor (HIF)-1α.
Scaringi R, Piccoli M, Papini N, Cirillo F, Conforti E, Bergante S, Tringali C, Garatti A, Gelfi C, Venerando B, Menicanti L, Tettamanti G, Anastasia L. Scaringi R, et al. J Biol Chem. 2013 Feb 1;288(5):3153-62. doi: 10.1074/jbc.M112.404327. Epub 2012 Dec 3. J Biol Chem. 2013. PMID: 23209287 Free PMC article.
The synthetic purine reversine selectively induces cell death of cancer cells.
Piccoli M, Palazzolo G, Conforti E, Lamorte G, Papini N, Creo P, Fania C, Scaringi R, Bergante S, Tringali C, Roncoroni L, Mazzoleni S, Doneda L, Galli R, Venerando B, Tettamanti G, Gelfi C, Anastasia L. Piccoli M, et al. Among authors: scaringi r. J Cell Biochem. 2012 Oct;113(10):3207-17. doi: 10.1002/jcb.24197. J Cell Biochem. 2012. PMID: 22615034
Chemoselective synthesis of sialic acid 1,7-lactones.
Allevi P, Rota P, Scaringi R, Colombo R, Anastasia M. Allevi P, et al. Among authors: scaringi r. J Org Chem. 2010 Aug 20;75(16):5542-8. doi: 10.1021/jo100732j. J Org Chem. 2010. PMID: 20704429
cAMP-dependent protein kinase regulates post-translational processing and expression of complex I subunits in mammalian cells.
Papa S, Scacco S, De Rasmo D, Signorile A, Papa F, Panelli D, Nicastro A, Scaringi R, Santeramo A, Roca E, Trentadue R, Larizza M. Papa S, et al. Among authors: scaringi r. Biochim Biophys Acta. 2010 Jun-Jul;1797(6-7):649-58. doi: 10.1016/j.bbabio.2010.03.013. Epub 2010 Mar 19. Biochim Biophys Acta. 2010. PMID: 20303927 Free article.