Scapozza L - Search Results

1

In Silico Driven Design and Synthesis of Rhodanine Derivatives as Novel Antibacterials Targeting the Enoyl Reductase InhA.

Slepikas L, Chiriano G, Perozzo R, Tardy S, Kranjc A, Patthey-Vuadens O, Ouertatani-Sakouhi H, Kicka S, Harrison CF, Scrignari T, Perron K, Hilbi H, Soldati T, Cosson P, Tarasevicius E, Scapozza L. Slepikas L, et al. Among authors: scapozza l. J Med Chem. 2016 Dec 22;59(24):10917-10928. doi: 10.1021/acs.jmedchem.5b01620. Epub 2016 Dec 9. J Med Chem. 2016. PMID: 26730986

2

Substrate diversity of herpes simplex virus thymidine kinase. Impact Of the kinematics of the enzyme.

Pilger BD, Perozzo R, Alber F, Wurth C, Folkers G, Scapozza L. Pilger BD, et al. Among authors: scapozza l. J Biol Chem. 1999 Nov 5;274(45):31967-73. doi: 10.1074/jbc.274.45.31967. J Biol Chem. 1999. PMID: 10542226 Free article.

3

Compulsory order of substrate binding to herpes simplex virus type 1 thymidine kinase. A calorimetric study.

Perozzo R, Jelesarov I, Bosshard HR, Folkers G, Scapozza L. Perozzo R, et al. Among authors: scapozza l. J Biol Chem. 2000 May 26;275(21):16139-45. doi: 10.1074/jbc.M000509200. J Biol Chem. 2000. PMID: 10747922 Free article.

4

Thermodynamics of protein-ligand interactions: history, presence, and future aspects.

Perozzo R, Folkers G, Scapozza L. Perozzo R, et al. Among authors: scapozza l. J Recept Signal Transduct Res. 2004 Feb;24(1-2):1-52. doi: 10.1081/rrs-120037896. J Recept Signal Transduct Res. 2004. PMID: 15344878 Review.

5

Recombinant expression and biochemical characterization of the unique elongating beta-ketoacyl-acyl carrier protein synthase involved in fatty acid biosynthesis of Plasmodium falciparum using natural and artificial substrates.

Lack G, Homberger-Zizzari E, Folkers G, Scapozza L, Perozzo R. Lack G, et al. Among authors: scapozza l. J Biol Chem. 2006 Apr 7;281(14):9538-46. doi: 10.1074/jbc.M509119200. Epub 2006 Feb 8. J Biol Chem. 2006. PMID: 16467310 Free article.

6

Inhibition of Plasmodium falciparum fatty acid biosynthesis: evaluation of FabG, FabZ, and FabI as drug targets for flavonoids.

Tasdemir D, Lack G, Brun R, Rüedi P, Scapozza L, Perozzo R. Tasdemir D, et al. Among authors: scapozza l. J Med Chem. 2006 Jun 1;49(11):3345-53. doi: 10.1021/jm0600545. J Med Chem. 2006. PMID: 16722653

7

Calpain-mediated cleavage of Atg5 switches autophagy to apoptosis.

Yousefi S, Perozzo R, Schmid I, Ziemiecki A, Schaffner T, Scapozza L, Brunner T, Simon HU. Yousefi S, et al. Among authors: scapozza l. Nat Cell Biol. 2006 Oct;8(10):1124-32. doi: 10.1038/ncb1482. Epub 2006 Sep 24. Nat Cell Biol. 2006. PMID: 16998475

8

Synthesis and evaluation of antiparasitic activities of new 4-[5-(4-phenoxyphenyl)-2H-pyrazol-3-yl]morpholine derivatives.

Kuettel S, Zambon A, Kaiser M, Brun R, Scapozza L, Perozzo R. Kuettel S, et al. Among authors: scapozza l. J Med Chem. 2007 Nov 15;50(23):5833-9. doi: 10.1021/jm700938n. Epub 2007 Oct 20. J Med Chem. 2007. PMID: 17949068

9

Adenosine Kinase of T. b. Rhodesiense identified as the putative target of 4-[5-(4-phenoxyphenyl)-2H-pyrazol-3-yl]morpholine using chemical proteomics.

Kuettel S, Mosimann M, Mäser P, Kaiser M, Brun R, Scapozza L, Perozzo R. Kuettel S, et al. Among authors: scapozza l. PLoS Negl Trop Dis. 2009 Aug 25;3(8):e506. doi: 10.1371/journal.pntd.0000506. PLoS Negl Trop Dis. 2009. PMID: 19707572 Free PMC article.

10

Single-molecule pulling simulations can discern active from inactive enzyme inhibitors.

Colizzi F, Perozzo R, Scapozza L, Recanatini M, Cavalli A. Colizzi F, et al. Among authors: scapozza l. J Am Chem Soc. 2010 Jun 2;132(21):7361-71. doi: 10.1021/ja100259r. J Am Chem Soc. 2010. PMID: 20462212

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