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Dual acting antioxidant A1 adenosine receptor agonists.
Gregg A, Bottle SE, Devine SM, Figler H, Linden J, White P, Pouton CW, Urmaliya V, Scammells PJ. Gregg A, et al. Among authors: scammells pj. Bioorg Med Chem Lett. 2007 Oct 1;17(19):5437-41. doi: 10.1016/j.bmcl.2007.07.035. Epub 2007 Jul 25. Bioorg Med Chem Lett. 2007. PMID: 17689079 Free article.
A novel highly selective adenosine A1 receptor agonist VCP28 reduces ischemia injury in a cardiac cell line and ischemia-reperfusion injury in isolated rat hearts at concentrations that do not affect heart rate.
Urmaliya VB, Pouton CW, Devine SM, Haynes JM, Warfe L, Scammells PJ, White PJ. Urmaliya VB, et al. Among authors: scammells pj. J Cardiovasc Pharmacol. 2010 Sep;56(3):282-92. doi: 10.1097/FJC.0b013e3181eb8563. J Cardiovasc Pharmacol. 2010. PMID: 20571427
Design strategies for bivalent ligands targeting GPCRs.
Shonberg J, Scammells PJ, Capuano B. Shonberg J, et al. Among authors: scammells pj. ChemMedChem. 2011 Jun 6;6(6):963-74. doi: 10.1002/cmdc.201100101. Epub 2011 Apr 21. ChemMedChem. 2011. PMID: 21520422 Review.
157 results