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IL-1β+ macrophages fuel pathogenic inflammation in pancreatic cancer.
Caronni N, La Terza F, Vittoria FM, Barbiera G, Mezzanzanica L, Cuzzola V, Barresi S, Pellegatta M, Canevazzi P, Dunsmore G, Leonardi C, Montaldo E, Lusito E, Dugnani E, Citro A, Ng MSF, Schiavo Lena M, Drago D, Andolfo A, Brugiapaglia S, Scagliotti A, Mortellaro A, Corbo V, Liu Z, Mondino A, Dellabona P, Piemonti L, Taveggia C, Doglioni C, Cappello P, Novelli F, Iannacone M, Ng LG, Ginhoux F, Crippa S, Falconi M, Bonini C, Naldini L, Genua M, Ostuni R. Caronni N, et al. Among authors: scagliotti a. Nature. 2023 Nov;623(7986):415-422. doi: 10.1038/s41586-023-06685-2. Epub 2023 Nov 1. Nature. 2023. PMID: 37914939 Free article.
The dark side of immunotherapy: pancreatic cancer.
Mucciolo G, Roux C, Scagliotti A, Brugiapaglia S, Novelli F, Cappello P. Mucciolo G, et al. Among authors: scagliotti a. Cancer Drug Resist. 2020 May 11;3(3):491-520. doi: 10.20517/cdr.2020.13. eCollection 2020. Cancer Drug Resist. 2020. PMID: 35582441 Free PMC article. Review.
Co-targeting triple-negative breast cancer cells and endothelial cells by metronomic chemotherapy inhibits cell regrowth and migration via downregulation of the FAK/VEGFR2/VEGF axis and autophagy/apoptosis activation.
Scagliotti A, Capizzi L, Cazzaniga ME, Ilari A, De Giorgi M, Cordani N, Gallazzi M, Bruno A, Pelosi G, Albini A, Lavitrano M, Grassilli E, Cerrito MG. Scagliotti A, et al. Front Oncol. 2022 Nov 30;12:998274. doi: 10.3389/fonc.2022.998274. eCollection 2022. Front Oncol. 2022. PMID: 36531071 Free PMC article.
LKB1 Deficiency Renders NSCLC Cells Sensitive to ERK Inhibitors.
Caiola E, Iezzi A, Tomanelli M, Bonaldi E, Scagliotti A, Colombo M, Guffanti F, Micotti E, Garassino MC, Minoli L, Scanziani E, Broggini M, Marabese M. Caiola E, et al. Among authors: scagliotti a. J Thorac Oncol. 2020 Mar;15(3):360-370. doi: 10.1016/j.jtho.2019.10.009. Epub 2019 Oct 18. J Thorac Oncol. 2020. PMID: 31634668 Free article.
Metronomic combination of Vinorelbine and 5Fluorouracil is able to inhibit triple-negative breast cancer cells. Results from the proof-of-concept VICTOR-0 study.
Cerrito MG, De Giorgi M, Pelizzoni D, Bonomo SM, Digiacomo N, Scagliotti A, Bugarin C, Gaipa G, Grassilli E, Lavitrano M, Giovannoni R, Bidoli P, Cazzaniga ME. Cerrito MG, et al. Among authors: scagliotti a. Oncotarget. 2018 Jun 8;9(44):27448-27459. doi: 10.18632/oncotarget.25422. eCollection 2018 Jun 8. Oncotarget. 2018. PMID: 29937997 Free PMC article.