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IL6/STAT3 Signaling Hijacks Estrogen Receptor α Enhancers to Drive Breast Cancer Metastasis.
Siersbæk R, Scabia V, Nagarajan S, Chernukhin I, Papachristou EK, Broome R, Johnston SJ, Joosten SEP, Green AR, Kumar S, Jones J, Omarjee S, Alvarez-Fernandez R, Glont S, Aitken SJ, Kishore K, Cheeseman D, Rakha EA, D'Santos C, Zwart W, Russell A, Brisken C, Carroll JS. Siersbæk R, et al. Among authors: scabia v. Cancer Cell. 2020 Sep 14;38(3):412-423.e9. doi: 10.1016/j.ccell.2020.06.007. Epub 2020 Jul 16. Cancer Cell. 2020. PMID: 32679107 Free PMC article.
A Preclinical Model for ERα-Positive Breast Cancer Points to the Epithelial Microenvironment as Determinant of Luminal Phenotype and Hormone Response.
Sflomos G, Dormoy V, Metsalu T, Jeitziner R, Battista L, Scabia V, Raffoul W, Delaloye JF, Treboux A, Fiche M, Vilo J, Ayyanan A, Brisken C. Sflomos G, et al. Among authors: scabia v. Cancer Cell. 2016 Mar 14;29(3):407-422. doi: 10.1016/j.ccell.2016.02.002. Epub 2016 Mar 3. Cancer Cell. 2016. PMID: 26947176 Free article.
C/EBPα mediates the growth inhibitory effect of progestins on breast cancer cells.
Nacht AS, Ferrari R, Zaurin R, Scabia V, Carbonell-Caballero J, Le Dily F, Quilez J, Leopoldi A, Brisken C, Beato M, Vicent GP. Nacht AS, et al. Among authors: scabia v. EMBO J. 2019 Sep 16;38(18):e101426. doi: 10.15252/embj.2018101426. Epub 2019 Aug 2. EMBO J. 2019. PMID: 31373033 Free PMC article.
Intraductal patient-derived xenografts of estrogen receptor α-positive breast cancer recapitulate the histopathological spectrum and metastatic potential of human lesions.
Fiche M, Scabia V, Aouad P, Battista L, Treboux A, Stravodimou A, Zaman K; RLS; Dormoy V, Ayyanan A, Sflomos G, Brisken C. Fiche M, et al. Among authors: scabia v. J Pathol. 2019 Mar;247(3):287-292. doi: 10.1002/path.5200. Epub 2018 Dec 27. J Pathol. 2019. PMID: 30430577 Free PMC article.
Patient-derived xenograft (PDX) models in basic and translational breast cancer research.
Dobrolecki LE, Airhart SD, Alferez DG, Aparicio S, Behbod F, Bentires-Alj M, Brisken C, Bult CJ, Cai S, Clarke RB, Dowst H, Ellis MJ, Gonzalez-Suarez E, Iggo RD, Kabos P, Li S, Lindeman GJ, Marangoni E, McCoy A, Meric-Bernstam F, Piwnica-Worms H, Poupon MF, Reis-Filho J, Sartorius CA, Scabia V, Sflomos G, Tu Y, Vaillant F, Visvader JE, Welm A, Wicha MS, Lewis MT. Dobrolecki LE, et al. Among authors: scabia v. Cancer Metastasis Rev. 2016 Dec;35(4):547-573. doi: 10.1007/s10555-016-9653-x. Cancer Metastasis Rev. 2016. PMID: 28025748 Free PMC article. Review.
Contraceptive progestins with androgenic properties stimulate breast epithelial cell proliferation.
Shamseddin M, De Martino F, Constantin C, Scabia V, Lancelot AS, Laszlo C, Ayyannan A, Battista L, Raffoul W, Gailloud-Matthieu MC, Bucher P, Fiche M, Ambrosini G, Sflomos G, Brisken C. Shamseddin M, et al. Among authors: scabia v. EMBO Mol Med. 2021 Jul 7;13(7):e14314. doi: 10.15252/emmm.202114314. Epub 2021 May 27. EMBO Mol Med. 2021. PMID: 34042278 Free PMC article.