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Enhanced Ca2+-channeling complex formation at the ER-mitochondria interface underlies the pathogenesis of alcohol-associated liver disease.
Thoudam T, Chanda D, Lee JY, Jung MK, Sinam IS, Kim BG, Park BY, Kwon WH, Kim HJ, Kim M, Lim CW, Lee H, Huh YH, Miller CA, Saxena R, Skill NJ, Huda N, Kusumanchi P, Ma J, Yang Z, Kim MJ, Mun JY, Harris RA, Jeon JH, Liangpunsakul S, Lee IK. Thoudam T, et al. Among authors: saxena r. Nat Commun. 2023 Mar 27;14(1):1703. doi: 10.1038/s41467-023-37214-4. Nat Commun. 2023. PMID: 36973273 Free PMC article.
Modulation of the Tryptophan Hydroxylase 1/Monoamine Oxidase-A/5-Hydroxytryptamine/5-Hydroxytryptamine Receptor 2A/2B/2C Axis Regulates Biliary Proliferation and Liver Fibrosis During Cholestasis.
Kyritsi K, Chen L, O'Brien A, Francis H, Hein TW, Venter J, Wu N, Ceci L, Zhou T, Zawieja D, Gashev AA, Meng F, Invernizzi P, Fabris L, Wu C, Skill NJ, Saxena R, Liangpunsakul S, Alpini G, Glaser SS. Kyritsi K, et al. Among authors: saxena r. Hepatology. 2020 Mar;71(3):990-1008. doi: 10.1002/hep.30880. Epub 2019 Oct 18. Hepatology. 2020. PMID: 31344280 Free PMC article.
Knockdown of vimentin reduces mesenchymal phenotype of cholangiocytes in the Mdr2-/- mouse model of primary sclerosing cholangitis (PSC).
Zhou T, Kyritsi K, Wu N, Francis H, Yang Z, Chen L, O'Brien A, Kennedy L, Ceci L, Meadows V, Kusumanchi P, Wu C, Baiocchi L, Skill NJ, Saxena R, Sybenga A, Xie L, Liangpunsakul S, Meng F, Alpini G, Glaser S. Zhou T, et al. Among authors: saxena r. EBioMedicine. 2019 Oct;48:130-142. doi: 10.1016/j.ebiom.2019.09.013. Epub 2019 Sep 12. EBioMedicine. 2019. PMID: 31522982 Free PMC article.
Hepatic Histopathology Among Excessive Drinkers Without Advanced Liver Disease.
Chang B, Huang A, Saxena R, Sun Y, Liu S, Zhou G, Li B, Teng G, Zhao J, Zhang W, Jiang Y, Han S, Yang Z, Zhao J, Zou Z, Liangpunsakul S. Chang B, et al. Among authors: saxena r. Alcohol Alcohol. 2021 Oct 29;56(6):669-677. doi: 10.1093/alcalc/agab017. Alcohol Alcohol. 2021. PMID: 33765150 Free PMC article.
2,481 results