Sawyers CL - Search Results

1

Development of a second-generation antiandrogen for treatment of advanced prostate cancer.

Tran C, Ouk S, Clegg NJ, Chen Y, Watson PA, Arora V, Wongvipat J, Smith-Jones PM, Yoo D, Kwon A, Wasielewska T, Welsbie D, Chen CD, Higano CS, Beer TM, Hung DT, Scher HI, Jung ME, Sawyers CL. Tran C, et al. Among authors: sawyers cl. Science. 2009 May 8;324(5928):787-90. doi: 10.1126/science.1168175. Epub 2009 Apr 9. Science. 2009. PMID: 19359544 Free PMC article. Clinical Trial.

2

Evidence for clonal outgrowth of androgen-independent prostate cancer cells from androgen-dependent tumors through a two-step process.

Craft N, Chhor C, Tran C, Belldegrun A, DeKernion J, Witte ON, Said J, Reiter RE, Sawyers CL. Craft N, et al. Among authors: sawyers cl. Cancer Res. 1999 Oct 1;59(19):5030-6. Cancer Res. 1999. PMID: 10519419

3

NF-kappa B activates prostate-specific antigen expression and is upregulated in androgen-independent prostate cancer.

Chen CD, Sawyers CL. Chen CD, et al. Among authors: sawyers cl. Mol Cell Biol. 2002 Apr;22(8):2862-70. doi: 10.1128/MCB.22.8.2862-2870.2002. Mol Cell Biol. 2002. PMID: 11909978 Free PMC article.

4

Growth inhibitory effects of the dual ErbB1/ErbB2 tyrosine kinase inhibitor PKI-166 on human prostate cancer xenografts.

Mellinghoff IK, Tran C, Sawyers CL. Mellinghoff IK, et al. Among authors: sawyers cl. Cancer Res. 2002 Sep 15;62(18):5254-9. Cancer Res. 2002. PMID: 12234993

5

MicroPET imaging of prostate cancer in LNCAP-SR39TK-GFP mouse xenografts.

Yang H, Berger F, Tran C, Gambhir SS, Sawyers CL. Yang H, et al. Among authors: sawyers cl. Prostate. 2003 Apr 1;55(1):39-47. doi: 10.1002/pros.10208. Prostate. 2003. PMID: 12640659

6

Myc-driven murine prostate cancer shares molecular features with human prostate tumors.

Ellwood-Yen K, Graeber TG, Wongvipat J, Iruela-Arispe ML, Zhang J, Matusik R, Thomas GV, Sawyers CL. Ellwood-Yen K, et al. Among authors: sawyers cl. Cancer Cell. 2003 Sep;4(3):223-38. doi: 10.1016/s1535-6108(03)00197-1. Cancer Cell. 2003. PMID: 14522256 Free article.

7

Molecular determinants of resistance to antiandrogen therapy.

Chen CD, Welsbie DS, Tran C, Baek SH, Chen R, Vessella R, Rosenfeld MG, Sawyers CL. Chen CD, et al. Among authors: sawyers cl. Nat Med. 2004 Jan;10(1):33-9. doi: 10.1038/nm972. Epub 2003 Dec 21. Nat Med. 2004. PMID: 14702632

8

Overriding imatinib resistance with a novel ABL kinase inhibitor.

Shah NP, Tran C, Lee FY, Chen P, Norris D, Sawyers CL. Shah NP, et al. Among authors: sawyers cl. Science. 2004 Jul 16;305(5682):399-401. doi: 10.1126/science.1099480. Science. 2004. PMID: 15256671

9

HER2/neu kinase-dependent modulation of androgen receptor function through effects on DNA binding and stability.

Mellinghoff IK, Vivanco I, Kwon A, Tran C, Wongvipat J, Sawyers CL. Mellinghoff IK, et al. Among authors: sawyers cl. Cancer Cell. 2004 Nov;6(5):517-27. doi: 10.1016/j.ccr.2004.09.031. Cancer Cell. 2004. PMID: 15542435 Free article.

10

Transcriptional regulation of a metastasis suppressor gene by Tip60 and beta-catenin complexes.

Kim JH, Kim B, Cai L, Choi HJ, Ohgi KA, Tran C, Chen C, Chung CH, Huber O, Rose DW, Sawyers CL, Rosenfeld MG, Baek SH. Kim JH, et al. Among authors: sawyers cl. Nature. 2005 Apr 14;434(7035):921-6. doi: 10.1038/nature03452. Nature. 2005. PMID: 15829968 Free article.

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