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α-Synuclein aggregation nucleates through liquid-liquid phase separation.
Ray S, Singh N, Kumar R, Patel K, Pandey S, Datta D, Mahato J, Panigrahi R, Navalkar A, Mehra S, Gadhe L, Chatterjee D, Sawner AS, Maiti S, Bhatia S, Gerez JA, Chowdhury A, Kumar A, Padinhateeri R, Riek R, Krishnamoorthy G, Maji SK. Ray S, et al. Among authors: sawner as. Nat Chem. 2020 Aug;12(8):705-716. doi: 10.1038/s41557-020-0465-9. Epub 2020 Jun 8. Nat Chem. 2020. PMID: 32514159
Effect of Disease-Associated P123H and V70M Mutations on β-Synuclein Fibrillation.
Sharma K, Mehra S, Sawner AS, Markam PS, Panigrahi R, Navalkar A, Chatterjee D, Kumar R, Kadu P, Patel K, Ray S, Kumar A, Maji SK. Sharma K, et al. Among authors: sawner as. ACS Chem Neurosci. 2020 Sep 16;11(18):2836-2848. doi: 10.1021/acschemneuro.0c00405. Epub 2020 Sep 6. ACS Chem Neurosci. 2020. PMID: 32833434
Modulating α-Synuclein Liquid-Liquid Phase Separation.
Sawner AS, Ray S, Yadav P, Mukherjee S, Panigrahi R, Poudyal M, Patel K, Ghosh D, Kummerant E, Kumar A, Riek R, Maji SK. Sawner AS, et al. Biochemistry. 2021 Dec 7;60(48):3676-3696. doi: 10.1021/acs.biochem.1c00434. Epub 2021 Aug 25. Biochemistry. 2021. PMID: 34431665
Intermolecular interactions underlie protein/peptide phase separation irrespective of sequence and structure at crowded milieu.
Poudyal M, Patel K, Gadhe L, Sawner AS, Kadu P, Datta D, Mukherjee S, Ray S, Navalkar A, Maiti S, Chatterjee D, Devi J, Bera R, Gahlot N, Joseph J, Padinhateeri R, Maji SK. Poudyal M, et al. Among authors: sawner as. Nat Commun. 2023 Oct 4;14(1):6199. doi: 10.1038/s41467-023-41864-9. Nat Commun. 2023. PMID: 37794023 Free PMC article.