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Development of a population pharmacokinetic/pharmacodynamic model for various oral paclitaxel formulations co-administered with ritonavir and thrombospondin-1 based on data from early phase clinical studies.
van Eijk M, Yu H, Sawicki E, de Weger VA, Nuijen B, Dorlo TPC, Beijnen JH, Huitema ADR. van Eijk M, et al. Among authors: sawicki e. Cancer Chemother Pharmacol. 2022 Jul;90(1):71-82. doi: 10.1007/s00280-022-04445-z. Epub 2022 Jul 7. Cancer Chemother Pharmacol. 2022. PMID: 35799067 Free PMC article.
A Phase 1 Dose-Escalation Study of Low-Dose Metronomic Treatment With Novel Oral Paclitaxel Formulations in Combination With Ritonavir in Patients With Advanced Solid Tumors.
de Weger VA, Vermunt MAC, Stuurman FE, Burylo AM, Damoiseaux D, Hendrikx JJMA, Sawicki E, Moes JJ, Huitema ADR, Nuijen B, Rosing H, Mergui-Roelvink M, Beijnen JH, Marchetti S. de Weger VA, et al. Among authors: sawicki e. Clin Pharmacol Drug Dev. 2021 Jun;10(6):607-621. doi: 10.1002/cpdd.880. Epub 2020 Oct 5. Clin Pharmacol Drug Dev. 2021. PMID: 33021083 Clinical Trial.
A Phase I Dose Escalation Study of Once-Weekly Oral Administration of Docetaxel as ModraDoc001 Capsule or ModraDoc006 Tablet in Combination with Ritonavir.
de Weger VA, Stuurman FE, Koolen SLW, Moes JJ, Hendrikx JJMA, Sawicki E, Thijssen B, Keessen M, Rosing H, Mergui-Roelvink M, Huitema ADR, Nuijen B, Beijnen JH, Schellens JHM, Marchetti S. de Weger VA, et al. Among authors: sawicki e. Clin Cancer Res. 2019 Sep 15;25(18):5466-5474. doi: 10.1158/1078-0432.CCR-17-2299. Epub 2019 Jun 19. Clin Cancer Res. 2019. PMID: 31217201 Clinical Trial.
RNA virus evasion of nonsense-mediated decay.
May JP, Yuan X, Sawicki E, Simon AE. May JP, et al. Among authors: sawicki e. PLoS Pathog. 2018 Nov 19;14(11):e1007459. doi: 10.1371/journal.ppat.1007459. eCollection 2018 Nov. PLoS Pathog. 2018. PMID: 30452463 Free PMC article.
A dose-escalation study of bi-daily once weekly oral docetaxel either as ModraDoc001 or ModraDoc006 combined with ritonavir.
de Weger VA, Stuurman FE, Hendrikx JJMA, Moes JJ, Sawicki E, Huitema ADR, Nuijen B, Thijssen B, Rosing H, Keessen M, Mergui-Roelvink M, Beijnen JH, Schellens JHM, Marchetti S. de Weger VA, et al. Among authors: sawicki e. Eur J Cancer. 2017 Nov;86:217-225. doi: 10.1016/j.ejca.2017.09.010. Epub 2017 Oct 12. Eur J Cancer. 2017. PMID: 29031170 Clinical Trial.
79 results