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TNF-α and α-synuclein fibrils differently regulate human astrocyte immune reactivity and impair mitochondrial respiration.
Russ K, Teku G, Bousset L, Redeker V, Piel S, Savchenko E, Pomeshchik Y, Savistchenko J, Stummann TC, Azevedo C, Collin A, Goldwurm S, Fog K, Elmer E, Vihinen M, Melki R, Roybon L. Russ K, et al. Among authors: savistchenko j. Cell Rep. 2021 Mar 23;34(12):108895. doi: 10.1016/j.celrep.2021.108895. Cell Rep. 2021. PMID: 33761362 Free article.
Structure of the prion Ure2p in protein fibrils assembled in vitro.
Fay N, Redeker V, Savistchenko J, Dubois S, Bousset L, Melki R. Fay N, et al. Among authors: savistchenko j. J Biol Chem. 2005 Nov 4;280(44):37149-58. doi: 10.1074/jbc.M506917200. Epub 2005 Aug 30. J Biol Chem. 2005. PMID: 16131495 Free article.
Pericytes take up and degrade α-synuclein but succumb to apoptosis under cellular stress.
Stevenson TJ, Johnson RH, Savistchenko J, Rustenhoven J, Woolf Z, Smyth LCD, Murray HC, Faull RLM, Correia J, Schweder P, Heppner P, Turner C, Melki R, Dieriks BV, Curtis MA, Dragunow M. Stevenson TJ, et al. Among authors: savistchenko j. Sci Rep. 2022 Oct 15;12(1):17314. doi: 10.1038/s41598-022-20261-0. Sci Rep. 2022. PMID: 36243723 Free PMC article.
17 results