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The live biotherapeutic Blautia stercoris MRx0006 attenuates social deficits, repetitive behaviour, and anxiety-like behaviour in a mouse model relevant to autism.
Sen P, Sherwin E, Sandhu K, Bastiaanssen TFS, Moloney GM, Golubeva A, Fitzgerald P, Paula Ventura Da Silva A, Chruścicka-Smaga B, Olavarría-Ramírez L, Druelle C, Campos D, Jayaprakash P, Rea K, Jeffery IB, Savignac H, Chetal S, Mulder I, Schellekens H, Dinan TG, Cryan JF. Sen P, et al. Among authors: savignac h. Brain Behav Immun. 2022 Nov;106:115-126. doi: 10.1016/j.bbi.2022.08.007. Epub 2022 Aug 19. Brain Behav Immun. 2022. PMID: 35995237 Free article.
GABAB(1) receptor subunit isoforms differentially regulate stress resilience.
O'Leary OF, Felice D, Galimberti S, Savignac HM, Bravo JA, Crowley T, El Yacoubi M, Vaugeois JM, Gassmann M, Bettler B, Dinan TG, Cryan JF. O'Leary OF, et al. Among authors: savignac hm. Proc Natl Acad Sci U S A. 2014 Oct 21;111(42):15232-7. doi: 10.1073/pnas.1404090111. Epub 2014 Oct 6. Proc Natl Acad Sci U S A. 2014. PMID: 25288769 Free PMC article.
Disturbance of the gut microbiota in early-life selectively affects visceral pain in adulthood without impacting cognitive or anxiety-related behaviors in male rats.
O'Mahony SM, Felice VD, Nally K, Savignac HM, Claesson MJ, Scully P, Woznicki J, Hyland NP, Shanahan F, Quigley EM, Marchesi JR, O'Toole PW, Dinan TG, Cryan JF. O'Mahony SM, et al. Among authors: savignac hm. Neuroscience. 2014 Sep 26;277:885-901. doi: 10.1016/j.neuroscience.2014.07.054. Epub 2014 Aug 1. Neuroscience. 2014. PMID: 25088912
19 results