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Influenza infection in suckling mice expands an NKT cell subset that protects against airway hyperreactivity.
Chang YJ, Kim HY, Albacker LA, Lee HH, Baumgarth N, Akira S, Savage PB, Endo S, Yamamura T, Maaskant J, Kitano N, Singh A, Bhatt A, Besra GS, van den Elzen P, Appelmelk B, Franck RW, Chen G, DeKruyff RH, Shimamura M, Illarionov P, Umetsu DT. Chang YJ, et al. Among authors: savage pb. J Clin Invest. 2011 Jan;121(1):57-69. doi: 10.1172/JCI44845. Epub 2010 Dec 13. J Clin Invest. 2011. PMID: 21157038 Free PMC article.
Innate lymphoid cells responding to IL-33 mediate airway hyperreactivity independently of adaptive immunity.
Kim HY, Chang YJ, Subramanian S, Lee HH, Albacker LA, Matangkasombut P, Savage PB, McKenzie AN, Smith DE, Rottman JB, DeKruyff RH, Umetsu DT. Kim HY, et al. Among authors: savage pb. J Allergy Clin Immunol. 2012 Jan;129(1):216-27.e1-6. doi: 10.1016/j.jaci.2011.10.036. Epub 2011 Nov 25. J Allergy Clin Immunol. 2012. PMID: 22119406 Free PMC article.
T-cell immunoglobulin and mucin domain 1 deficiency eliminates airway hyperreactivity triggered by the recognition of airway cell death.
Kim HY, Chang YJ, Chuang YT, Lee HH, Kasahara DI, Martin T, Hsu JT, Savage PB, Shore SA, Freeman GJ, Dekruyff RH, Umetsu DT. Kim HY, et al. Among authors: savage pb. J Allergy Clin Immunol. 2013 Aug;132(2):414-25.e6. doi: 10.1016/j.jaci.2013.03.025. Epub 2013 May 11. J Allergy Clin Immunol. 2013. PMID: 23672783 Free PMC article.
A natural killer T-cell subset that protects against airway hyperreactivity.
Chuang YT, Leung K, Chang YJ, DeKruyff RH, Savage PB, Cruse R, Benoit C, Elewaut D, Baumgarth N, Umetsu DT. Chuang YT, et al. Among authors: savage pb. J Allergy Clin Immunol. 2019 Feb;143(2):565-576.e7. doi: 10.1016/j.jaci.2018.03.022. Epub 2018 May 29. J Allergy Clin Immunol. 2019. PMID: 29852257
Glycolipid activation of invariant T cell receptor+ NK T cells is sufficient to induce airway hyperreactivity independent of conventional CD4+ T cells.
Meyer EH, Goya S, Akbari O, Berry GJ, Savage PB, Kronenberg M, Nakayama T, DeKruyff RH, Umetsu DT. Meyer EH, et al. Among authors: savage pb. Proc Natl Acad Sci U S A. 2006 Feb 21;103(8):2782-7. doi: 10.1073/pnas.0510282103. Epub 2006 Feb 14. Proc Natl Acad Sci U S A. 2006. PMID: 16478801 Free PMC article.
203 results