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A comprehensive platform for analyzing longitudinal multi-omics data.
Vasaikar SV, Savage AK, Gong Q, Swanson E, Talla A, Lord C, Heubeck AT, Reading J, Graybuck LT, Meijer P, Torgerson TR, Skene PJ, Bumol TF, Li XJ. Vasaikar SV, et al. Among authors: savage ak. Nat Commun. 2023 Mar 27;14(1):1684. doi: 10.1038/s41467-023-37432-w. Nat Commun. 2023. PMID: 36973282 Free PMC article.
Multimodal analysis for human ex vivo studies shows extensive molecular changes from delays in blood processing.
Savage AK, Gutschow MV, Chiang T, Henderson K, Green R, Chaudhari M, Swanson E, Heubeck AT, Kondza N, Burley KC, Genge PC, Lord C, Smith T, Thomson Z, Beaubien A, Johnson E, Goldy J, Bolouri H, Buckner JH, Meijer P, Coffey EM, Skene PJ, Torgerson TR, Li XJ, Bumol TF. Savage AK, et al. iScience. 2021 Apr 15;24(5):102404. doi: 10.1016/j.isci.2021.102404. eCollection 2021 May 21. iScience. 2021. PMID: 34113805 Free PMC article.
Trimodal single-cell profiling reveals a novel pediatric CD8αα+ T cell subset and broad age-related molecular reprogramming across the T cell compartment.
Thomson Z, He Z, Swanson E, Henderson K, Phalen C, Zaim SR, Pebworth MP, Okada LY, Heubeck AT, Roll CR, Hernandez V, Weiss M, Genge PC, Reading J, Giles JR, Manne S, Dougherty J, Jasen CJ, Greenplate AR, Becker LA, Graybuck LT, Vasaikar SV, Szeto GL, Savage AK, Speake C, Buckner JH, Li XJ, Bumol TF, Wherry EJ, Torgerson TR, Vella LA, Henrickson SE, Skene PJ, Gustafson CE. Thomson Z, et al. Among authors: savage ak. Nat Immunol. 2023 Nov;24(11):1947-1959. doi: 10.1038/s41590-023-01641-8. Epub 2023 Oct 16. Nat Immunol. 2023. PMID: 37845489 Free PMC article.
Author Correction: Trimodal single-cell profiling reveals a novel pediatric CD8αα+ T cell subset and broad age-related molecular reprogramming across the T cell compartment.
Thomson Z, He Z, Swanson E, Henderson K, Phalen C, Zaim SR, Pebworth MP, Okada LY, Heubeck AT, Roll CR, Hernandez V, Weiss M, Genge PC, Reading J, Giles JR, Manne S, Dougherty J, Jasen CJ, Greenplate AR, Becker LA, Graybuck LT, Vasaikar SV, Szeto GL, Savage AK, Speake C, Buckner JH, Li XJ, Bumol TF, Wherry EJ, Torgerson TR, Vella LA, Henrickson SE, Skene PJ, Gustafson CE. Thomson Z, et al. Among authors: savage ak. Nat Immunol. 2024 Mar;25(3):577. doi: 10.1038/s41590-024-01757-5. Nat Immunol. 2024. PMID: 38267693 Free PMC article. No abstract available.
A simple strategy for sample annotation error detection in cytometry datasets.
Smithmyer ME, Wiedeman AE, Skibinski DAG, Savage AK, Acosta-Vega C, Scheiding S, Gersuk VH, O'Rourke C, Long SA, Buckner JH, Speake C. Smithmyer ME, et al. Among authors: savage ak. Cytometry A. 2022 Apr;101(4):351-360. doi: 10.1002/cyto.a.24525. Epub 2021 Dec 29. Cytometry A. 2022. PMID: 34967113 Free article.
Abatacept increases T cell exhaustion in early RA individuals who carry HLA risk alleles.
Long SA, Muir VS, Jones BE, Wall VZ, Ylescupidez A, Hocking AM, Pribitzer S, Thorpe J, Fuchs B, Wiedeman AE, Tatum M, Lambert K, Uchtenhagen H, Speake C, Ng B, Heubeck AT, Torgerson TR, Savage AK, Maldonado MA, Ray N, Khaychuk V, Liu J, Linsley PS, Buckner JH. Long SA, et al. Among authors: savage ak. Front Immunol. 2024 Apr 8;15:1383110. doi: 10.3389/fimmu.2024.1383110. eCollection 2024. Front Immunol. 2024. PMID: 38650930 Free PMC article.
A stromal progenitor and ILC2 niche promotes muscle eosinophilia and fibrosis-associated gene expression.
Kastenschmidt JM, Coulis G, Farahat PK, Pham P, Rios R, Cristal TT, Mannaa AH, Ayer RE, Yahia R, Deshpande AA, Hughes BS, Savage AK, Giesige CR, Harper SQ, Locksley RM, Mozaffar T, Villalta SA. Kastenschmidt JM, et al. Among authors: savage ak. Cell Rep. 2021 Apr 13;35(2):108997. doi: 10.1016/j.celrep.2021.108997. Cell Rep. 2021. PMID: 33852849 Free PMC article.
21 results