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A Novel l-Asparaginase with low l-Glutaminase Coactivity Is Highly Efficacious against Both T- and B-cell Acute Lymphoblastic Leukemias In Vivo.
Nguyen HA, Su Y, Zhang JY, Antanasijevic A, Caffrey M, Schalk AM, Liu L, Rondelli D, Oh A, Mahmud DL, Bosland MC, Kajdacsy-Balla A, Peirs S, Lammens T, Mondelaers V, De Moerloose B, Goossens S, Schlicht MJ, Kabirov KK, Lyubimov AV, Merrill BJ, Saunthararajah Y, Van Vlierberghe P, Lavie A. Nguyen HA, et al. Among authors: saunthararajah y. Cancer Res. 2018 Mar 15;78(6):1549-1560. doi: 10.1158/0008-5472.CAN-17-2106. Epub 2018 Jan 17. Cancer Res. 2018. PMID: 29343523 Free PMC article.
Fludarabine/i.v. BU conditioning regimen: myeloablative, reduced intensity or both?
Chunduri S, Dobogai LC, Peace D, Saunthararajah Y, Quigley J, Chen YH, Mahmud N, Hurter E, Beri R, Rondelli D. Chunduri S, et al. Among authors: saunthararajah y. Bone Marrow Transplant. 2008 Jun;41(11):935-40. doi: 10.1038/bmt.2008.13. Epub 2008 Feb 11. Bone Marrow Transplant. 2008. PMID: 18264144 Clinical Trial.
Noncytotoxic differentiation treatment of renal cell cancer.
Negrotto S, Hu Z, Alcazar O, Ng KP, Triozzi P, Lindner D, Rini B, Saunthararajah Y. Negrotto S, et al. Among authors: saunthararajah y. Cancer Res. 2011 Feb 15;71(4):1431-41. doi: 10.1158/0008-5472.CAN-10-2422. Epub 2011 Feb 8. Cancer Res. 2011. PMID: 21303982 Free PMC article.
Comparable kinetics of myeloablation between fludarabine/full-dose busulfan and fludarabine/melphalan conditioning regimens in allogeneic peripheral blood stem cell transplantation.
Chunduri S, Dobogai LC, Peace D, Saunthararajah Y, Chen HY, Mahmud N, Quigley J, Hoffman R, Jessop E, Beri R, Rondelli D. Chunduri S, et al. Among authors: saunthararajah y. Bone Marrow Transplant. 2006 Oct;38(7):477-82. doi: 10.1038/sj.bmt.1705480. Bone Marrow Transplant. 2006. PMID: 16980995 Clinical Trial.
Increased CDA expression/activity in males contributes to decreased cytidine analog half-life and likely contributes to worse outcomes with 5-azacytidine or decitabine therapy.
Mahfouz RZ, Jankowska A, Ebrahem Q, Gu X, Visconte V, Tabarroki A, Terse P, Covey J, Chan K, Ling Y, Engelke KJ, Sekeres MA, Tiu R, Maciejewski J, Radivoyevitch T, Saunthararajah Y. Mahfouz RZ, et al. Among authors: saunthararajah y. Clin Cancer Res. 2013 Feb 15;19(4):938-48. doi: 10.1158/1078-0432.CCR-12-1722. Epub 2013 Jan 3. Clin Cancer Res. 2013. PMID: 23287564 Free PMC article.
163 results