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Page 1
Design of Phthalazinone Amide Histamine H1 Receptor Antagonists for Use in Rhinitis.
Procopiou PA, Ford AJ, Gore PM, Looker BE, Hodgson ST, Holmes DS, Vile S, Clark KL, Saunders KA, Slack RJ, Rowedder JE, Watts CJ. Procopiou PA, et al. Among authors: saunders ka. ACS Med Chem Lett. 2017 Apr 21;8(5):577-581. doi: 10.1021/acsmedchemlett.7b00112. eCollection 2017 May 11. ACS Med Chem Lett. 2017. PMID: 28523114 Free PMC article.
Identification of selective 8-(piperidin-4-yloxy)quinoline sulfone and sulfonamide histamine H1 receptor antagonists for use in allergic rhinitis.
Procopiou PA, Ford AJ, Gore PM, Hancock AP, Hodgson ST, Holmes DS, Looker BE, Vile S, Clark KL, Saunders KA, Slack RJ, Watts CJ. Procopiou PA, et al. Among authors: saunders ka. Bioorg Med Chem Lett. 2017 Nov 1;27(21):4914-4919. doi: 10.1016/j.bmcl.2017.09.020. Epub 2017 Sep 9. Bioorg Med Chem Lett. 2017. PMID: 28958623
Obesity and disease severity magnify disturbed microbiome-immune interactions in asthma patients.
Michalovich D, Rodriguez-Perez N, Smolinska S, Pirozynski M, Mayhew D, Uddin S, Van Horn S, Sokolowska M, Altunbulakli C, Eljaszewicz A, Pugin B, Barcik W, Kurnik-Lucka M, Saunders KA, Simpson KD, Schmid-Grendelmeier P, Ferstl R, Frei R, Sievi N, Kohler M, Gajdanowicz P, Graversen KB, Lindholm Bøgh K, Jutel M, Brown JR, Akdis CA, Hessel EM, O'Mahony L. Michalovich D, et al. Among authors: saunders ka. Nat Commun. 2019 Dec 13;10(1):5711. doi: 10.1038/s41467-019-13751-9. Nat Commun. 2019. PMID: 31836714 Free PMC article.
Rhinovirus-induced Human Lung Tissue Responses Mimic Chronic Obstructive Pulmonary Disease and Asthma Gene Signatures.
Wronski S, Beinke S, Obernolte H, Belyaev NN, Saunders KA, Lennon MG, Schaudien D, Braubach P, Jonigk D, Warnecke G, Zardo P, Fieguth HG, Wilkens L, Braun A, Hessel EM, Sewald K. Wronski S, et al. Among authors: saunders ka. Am J Respir Cell Mol Biol. 2021 Nov;65(5):544-554. doi: 10.1165/rcmb.2020-0337OC. Am J Respir Cell Mol Biol. 2021. PMID: 34181859 Free PMC article.
Exploring PI3Kδ Molecular Pathways in Stable COPD and Following an Acute Exacerbation, Two Randomized Controlled Trials.
Begg M, Hamblin JN, Jarvis E, Bradley G, Mark S, Michalovich D, Lennon M, Wajdner HE, Amour A, Wilson R, Saunders K, Tanaka R, Arai S, Tang T, Van Holsbeke C, De Backer J, Vos W, Titlestad IL, FitzGerald JM, Killian K, Bourbeau J, Poirier C, Maltais F, Cahn A, Hessel EM. Begg M, et al. Int J Chron Obstruct Pulmon Dis. 2021 Jun 3;16:1621-1636. doi: 10.2147/COPD.S309303. eCollection 2021. Int J Chron Obstruct Pulmon Dis. 2021. PMID: 34113094 Free PMC article.
Obesity dysregulates the pulmonary antiviral immune response.
Almond M, Farne HA, Jackson MM, Jha A, Katsoulis O, Pitts O, Tunstall T, Regis E, Dunning J, Byrne AJ, Mallia P, Kon OM, Saunders KA, Simpson KD, Snelgrove RJ, Openshaw PJM, Edwards MR, Barclay WS, Heaney LM, Johnston SL, Singanayagam A. Almond M, et al. Among authors: saunders ka. Nat Commun. 2023 Oct 19;14(1):6607. doi: 10.1038/s41467-023-42432-x. Nat Commun. 2023. PMID: 37857661 Free PMC article.
29 results