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A robotic multidimensional directed evolution approach applied to fluorescent voltage reporters.
Piatkevich KD, Jung EE, Straub C, Linghu C, Park D, Suk HJ, Hochbaum DR, Goodwin D, Pnevmatikakis E, Pak N, Kawashima T, Yang CT, Rhoades JL, Shemesh O, Asano S, Yoon YG, Freifeld L, Saulnier JL, Riegler C, Engert F, Hughes T, Drobizhev M, Szabo B, Ahrens MB, Flavell SW, Sabatini BL, Boyden ES. Piatkevich KD, et al. Among authors: saulnier jl. Nat Chem Biol. 2018 Apr;14(4):352-360. doi: 10.1038/s41589-018-0004-9. Epub 2018 Feb 26. Nat Chem Biol. 2018. PMID: 29483642 Free PMC article.
All-optical electrophysiology in mammalian neurons using engineered microbial rhodopsins.
Hochbaum DR, Zhao Y, Farhi SL, Klapoetke N, Werley CA, Kapoor V, Zou P, Kralj JM, Maclaurin D, Smedemark-Margulies N, Saulnier JL, Boulting GL, Straub C, Cho YK, Melkonian M, Wong GK, Harrison DJ, Murthy VN, Sabatini BL, Boyden ES, Campbell RE, Cohen AE. Hochbaum DR, et al. Among authors: saulnier jl. Nat Methods. 2014 Aug;11(8):825-33. doi: 10.1038/nmeth.3000. Epub 2014 Jun 22. Nat Methods. 2014. PMID: 24952910 Free PMC article.
CRISPR/Cas9-mediated gene knock-down in post-mitotic neurons.
Straub C, Granger AJ, Saulnier JL, Sabatini BL. Straub C, et al. Among authors: saulnier jl. PLoS One. 2014 Aug 20;9(8):e105584. doi: 10.1371/journal.pone.0105584. eCollection 2014. PLoS One. 2014. PMID: 25140704 Free PMC article.
27 results