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Endoplasmic reticulum stress in the intestinal epithelium initiates purine metabolite synthesis and promotes Th17 cell differentiation in the gut.
Duan J, Matute JD, Unger LW, Hanley T, Schnell A, Lin X, Krupka N, Griebel P, Lambden C, Sit B, Grootjans J, Pyzik M, Sommer F, Kaiser S, Falk-Paulsen M, Grasberger H, Kao JY, Fuhrer T, Li H, Paik D, Lee Y, Refetoff S, Glickman JN, Paton AW, Bry L, Paton JC, Sauer U, Macpherson AJ, Rosenstiel P, Kuchroo VK, Waldor MK, Huh JR, Kaser A, Blumberg RS. Duan J, et al. Among authors: sauer u. Immunity. 2023 May 9;56(5):1115-1131.e9. doi: 10.1016/j.immuni.2023.02.018. Epub 2023 Mar 13. Immunity. 2023. PMID: 36917985 Free PMC article.
Plasticity of the adult human small intestinal stoma microbiota.
Yilmaz B, Fuhrer T, Morgenthaler D, Krupka N, Wang D, Spari D, Candinas D, Misselwitz B, Beldi G, Sauer U, Macpherson AJ. Yilmaz B, et al. Among authors: sauer u. Cell Host Microbe. 2022 Dec 14;30(12):1773-1787.e6. doi: 10.1016/j.chom.2022.10.002. Epub 2022 Oct 31. Cell Host Microbe. 2022. PMID: 36318918 Free article.
Secrets of microbiota drug metabolism.
Macpherson AJ, Sauer U. Macpherson AJ, et al. Among authors: sauer u. Nat Med. 2023 Mar;29(3):537-538. doi: 10.1038/s41591-023-02227-5. Nat Med. 2023. PMID: 36823300 No abstract available.
Arginine reprograms metabolism in liver cancer via RBM39.
Mossmann D, Müller C, Park S, Ryback B, Colombi M, Ritter N, Weißenberger D, Dazert E, Coto-Llerena M, Nuciforo S, Blukacz L, Ercan C, Jimenez V, Piscuoglio S, Bosch F, Terracciano LM, Sauer U, Heim MH, Hall MN. Mossmann D, et al. Among authors: sauer u. Cell. 2023 Nov 9;186(23):5068-5083.e23. doi: 10.1016/j.cell.2023.09.011. Epub 2023 Oct 6. Cell. 2023. PMID: 37804830 Free PMC article.
Targeting the Main Protease (Mpro, nsp5) by Growth of Fragment Scaffolds Exploiting Structure-Based Methodologies.
Altincekic N, Jores N, Löhr F, Richter C, Ehrhardt C, Blommers MJJ, Berg H, Öztürk S, Gande SL, Linhard V, Orts J, Abi Saad MJ, Bütikofer M, Kaderli J, Karlsson BG, Brath U, Hedenström M, Gröbner G, Sauer UH, Perrakis A, Langer J, Banci L, Cantini F, Fragai M, Grifagni D, Barthel T, Wollenhaupt J, Weiss MS, Robertson A, Bax A, Sreeramulu S, Schwalbe H. Altincekic N, et al. Among authors: sauer uh. ACS Chem Biol. 2024 Feb 16;19(2):563-574. doi: 10.1021/acschembio.3c00720. Epub 2024 Jan 17. ACS Chem Biol. 2024. PMID: 38232960 Free PMC article.
Revitalizing antibiotic discovery and development through in vitro modelling of in-patient conditions.
Sollier J, Basler M, Broz P, Dittrich PS, Drescher K, Egli A, Harms A, Hierlemann A, Hiller S, King CG, McKinney JD, Moran-Gilad J, Neher RA, Page MGP, Panke S, Persat A, Picotti P, Rentsch KM, Rivera-Fuentes P, Sauer U, Stolz D, Tschudin-Sutter S, van Delden C, van Nimwegen E, Veening JW, Zampieri M, Zinkernagel AS, Khanna N, Bumann D, Jenal U, Dehio C. Sollier J, et al. Among authors: sauer u. Nat Microbiol. 2024 Jan;9(1):1-3. doi: 10.1038/s41564-023-01566-w. Nat Microbiol. 2024. PMID: 38177300 No abstract available.
515 results